95969-90-7

Basic information

• Product Name: 2-Propynamide, N,N-dibutyl-3-phenyl-
• CAS NO: 95969-90-7
• Molecular Formula: C17H23NO
• Molecular Weight: 257.376
• Mol File: 95969-90-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Propynamide, N,N-dibutyl-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynamide, N,N-dibutyl-3-phenyl-(95969-90-7)
• EPA Substance Registry System: 2-Propynamide, N,N-dibutyl-3-phenyl-(95969-90-7)

Safety Data

• Hazardous Substances Data: 95969-90-7(Hazardous Substances Data)

Upstream product

• 2170-06-1 1-Phenyl-2-(trimethylsilyl)acetylene 
• 111-92-2 dibutylamine 
• 201230-82-2 carbon monoxide 
• 536-74-3 phenylacetylene 
• 102-82-9 tributyl-amine 
• 761-65-9 N,N-dibutylformamide 
• 84452-21-1 2-hydroxy-4-phenyl-3-butynenitrile 

Relevant articles and documents

Copper-Catalyzed Carbamoylation of Terminal Alkynes with Formamides via Cross-Dehydrogenative Coupling

An efficient approach for direct carbamoylation of terminal alkynes with formamides affording propiolamides has been developed by copper-catalyzed oxidative cross coupling of C(sp)-H and C(sp2)-H bonds in the presence of a pincer ligand with tw

Palladium-Catalyzed Oxidative N-Dealkylation/Carbonylation of Tertiary Amines with Alkynes to α,β-Alkynylamides

The first highly effective Pd/C-catalyzed oxidative N-dealkylation/carbonylation of various aliphatic as well as cyclic tertiary amines with alkynes has been described. The selective sp3 C-N bond activation of tertiary amines at the less steric side using O2 as a sole oxidant and a plausible reaction pathway for the reaction are discussed. The general and operationally simple methodology provides an alternative for the synthesis of a wide range of alk-2-ynamide derivatives under mild conditions. The present protocol is ecofriendly and practical, and it shows significant recyclability.

2-HYDROXY-4-PHENYL-3-BUTYNENITRILE IN SELECTIVE OXIDATION

The oxidation of 2-hydroxy-4-phenyl-3-butynenitrile with active manganese(IV) oxide is accompanied by the intermediate formation of the unstable 2-oxo-4-phenyl-3-butynenitrile, in which the cyano group is substituted by the residue of the nucleophile present in the reaction.The reaction of 2-hydroxy-4-phenyl-3-butynenitrile with secondary amines in absolute ether is accompanied by isomerization to 2-oxo-4-phenyl-3-butenenitrile with subsequent substitution of the cyano group by the amino group.