95969-91-8Relevant articles and documents
N-triflyl-propiolamides: Preparation and transamidation reactions
Fiore, Vito A.,Maas, Gerhard
, p. 3586 - 3595 (2019/05/27)
N-Trifluoromethylsulfonyl-propiolamides have been prepared by two methods: a) N-triflation of secondary acetylenic carboxanilides, prepared in two steps from terminal alkynes, with triflic anhydride (Tf2O) and b) from terminal alkynes and an aryl or alkyl isocyanate followed by Tf2O in a consecutive one-pot reaction. The title compounds are bench-stable and insensitive to water and alcohols but amenable to transamidation reactions with a wide range of amine nucleophiles. Conversely, they are excellent reagents for the propynoylation of ammonia, primary and secondary amines, anilines, and hydrazines.
Silver-Promoted Synthesis of 5-[(Pentafluorosulfanyl)methyl]-2-oxazolines
Gilbert, Audrey,Bertrand, Xavier,Paquin, Jean-Fran?ois
supporting information, p. 7257 - 7260 (2018/11/23)
The synthesis of 5-[(pentafluorosulfanyl)methyl]-2-oxazolines is reported. The use of a silver promoter allows the intramolecular cyclization of N-[2-chloro-3-(pentafluorosulfanyl)propyl]amide to occur without elimination of the chlorine atom, a reaction
Structural factors affecting the selectivities in the palladium(II) catalyzed cyclization of N-alkenyl-2-alkynamides
Jiang, Huanfeng,Ma, Shengming,Zhu, Guoxin,Lu, Xiyan
, p. 10945 - 10954 (2007/10/03)
Palladium catalyzed cyclization of N-alkenyl 2-alkynamides occurred smoothly in the presence of CuCl2 and LiCl affording α-chloroalkylidene-γ-butyrolactams and α-chloroalkylidene-δ-valerolactams stereoselectively. The regioselectivity of the in