959866-77-4

Basic information

• Product Name: 4,6-dideoxy-4-(5-fluorocytosin-1-yl)-6-acetylamino-2,5-anhydro-L-mannofuranose dimethylacetal
• CAS NO: 959866-77-4
• Molecular Weight: 360.342
• Mol File: 959866-77-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,6-dideoxy-4-(5-fluorocytosin-1-yl)-6-acetylamino-2,5-anhydro-L-mannofuranose dimethylacetal(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-dideoxy-4-(5-fluorocytosin-1-yl)-6-acetylamino-2,5-anhydro-L-mannofuranose dimethylacetal(959866-77-4)
• EPA Substance Registry System: 4,6-dideoxy-4-(5-fluorocytosin-1-yl)-6-acetylamino-2,5-anhydro-L-mannofuranose dimethylacetal(959866-77-4)

Safety Data

• Hazardous Substances Data: 959866-77-4(Hazardous Substances Data)

Upstream product

• 959866-73-0 3-O-methanesulfonyl-4-O-acetyl-6-deoxy-6-acetylamino-2,5-anhydro-L-idofuranose dimethylacetal 
• 959866-72-9 3-O-methanesulfonyl-4-O-acetyl-6-deoxy-6-azido-2,5-anhydro-L-idofuranose dimethylacetal 
• 959866-71-8 3,6-di-O-methanesulfonyl-4-O-acetyl-2,5-anhydro-L-idofuranose dimethylacetal 
• 52628-70-3 3,6-di-O-methanesulfonyl-2,5-anhydro-L-idofuranose dimethylacetal 
• 959866-74-1 6-deoxy-6-acetylamino-2,5:3,4-dianhydro-L-talose dimethylacetal 
• 2022-85-7 Flucytosine 

Relevant articles and documents

A concise synthesis of 4,6-dideoxy-4-base-6-amino-2,5-anhydro-l-mannitols

3,6-Di-O-methanesulfonyl-2,5-anhydro-l-idofuranose dimethyl acetal 9 was reacted with NaN3 in DMF to give 6-azido substituted carbohydrate 10 selectively. A series of 6-amino-isonucleosides 4a-d were synthesized by the reaction of nucleobases with epoxide 13, followed by hydrolysis, reduction, and deprotection, in good yield.