960128-64-7

Basic information

• Product Name: (R)-1-Amino-8-(diphenylphosphino)-1,2,3,4-tetrahydronaphthalene, min. 97%
• Synonyms: (R)-1-Amino-8-(diphenylphosphino)-1,2,3,4-tetrahydronaphthalene, min. 97%;(R)-8-(Diphenylphosphino)-1,2,3,4-tetrahydronaphthalen-1-aMine;(R)-1-AMino-8-(diphenylphosphino)-1,2,3,4-tetrahydronaphthalene;(R)-8-(Diphenylphosphino)-1,2,3,4-tetrahydronaphthalen-1-aMi;(R)-(-)-8-Diphenylphosphino-1,2,3,4-tetrahydro-1-naphthylaMine, 97+%;(1R)-8-(Diphenylphosphino)-1,2,3,4-tetrahydro-1-naphthalenamine
• CAS NO: 960128-64-7
• Molecular Formula: C₂₂H₂₂NP
• Molecular Weight: 331.390541
• Product Categories: Chiral Phosphine
• Mol File: 960128-64-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 120-127℃
• Appearance: White to tan/Crystalline Powder or Crystals
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Sensitive: Air Sensitive
• CAS DataBase Reference: (R)-1-Amino-8-(diphenylphosphino)-1,2,3,4-tetrahydronaphthalene, min. 97%(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-Amino-8-(diphenylphosphino)-1,2,3,4-tetrahydronaphthalene, min. 97%(960128-64-7)
• EPA Substance Registry System: (R)-1-Amino-8-(diphenylphosphino)-1,2,3,4-tetrahydronaphthalene, min. 97%(960128-64-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• RIDADR: UN 3335
• WGK Germany: 3
• Hazardous Substances Data: 960128-64-7(Hazardous Substances Data)

Usage

General Description

(R)-1-Amino-8-(diphenylphosphino)-1,2,3,4-tetrahydronaphthalene, min. 97% is a chemical compound that is at least 97% pure and consists of a tetrahydronaphthalene molecule with an amino group and a diphenylphosphino group attached to it. (R)-1-Amino-8-(diphenylphosphino)-1,2,3,4-tetrahydronaphthalene, min. 97% is commonly used in organic synthesis and catalysis due to its chiral nature and ability to participate in various chemical reactions. It can be used as a ligand to form coordination complexes with transition metals, which can then be used to catalyze a variety of asymmetric reactions. The high purity of this compound makes it suitable for research and industrial applications where precise control over chemical reactions is necessary.

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 100-58-3 phenylmagnesium bromide 
• 1451012-53-5 5-bromo-1,2-dihydronaphthalene 
• 23357-46-2 (R)-1,2,3,4-Tetrahydro-1-naphthylamine 

Downstream Products

• 1193615-45-0 C₃₄H₃₁NP₂ 

Relevant articles and documents

COPPER CATALYZED HALOGENATON AND REACTION PRODUCTS

A Cu(I)-catalyzed 1,3-halogen migration reaction effectively recycles an activating group by transferring a halogen from an sp2 to a benzylic carbon with good enantioselectivity and concomitant borylation of the Ar-halo bond. The resulting enantio-enriched benzyl halide can be reacted in the same vessel under a variety of conditions to form an additional carbon-heteroatom or carbon-carbon bond while maintaining high ee. The reaction can be used to efficiently prepare novel compounds and intermediates for the preparation of therapeutics and ligands for catalysis.

Modular phosphine-aminophosphine ligands based on chiral 1,2,3,4-tetrahydro-1-naphthylamine backbone: A new class of practical ligands for enantioselective hydrogenations

A series of new chiral phosphine-aminophosphine ligands [(R)-HW-Phos] has been prepared from (R)-1,2,3,4-tetrahydro-1-naphthylamine through a two-step procedure, and successfully applied in the rhodium-catalyzed asymmetric hydrogenation of various functionalized olefins such as α-enol ester phosphonates, α-enamido phosphonates, (Z)-β-(acylamino)acrylates and so on. Excellent enantioselectivities have been achieved in the hydrogenation of most substrates tested, demonstrating the high potential of these newly developed phosphine-aminophosphine ligands in asymmetric catalysis. The present research also discloses that these newly developed phosphine-aminophosphine ligands are more efficient than that derived from (S)-1-phenylethylamine, suggesting that the increased rigidity conferred by a cyclohexyl fragment in these phosphine-aminophosphine ligands has a positive effect in the asymmetric induction.