96013-00-2 Usage
General Description
Uridine 5'-triphosphate, ammonium salt is a biochemical compound consisting of uridine, a nucleoside, and three phosphate groups, along with an ammonium salt. It plays a crucial role in the biosynthesis of nucleic acids, as it serves as a substrate for RNA and DNA synthesis and is involved in cellular communication and energy transfer processes. Uridine 5'-triphosphate, ammonium salt is also involved in the regulation of neurotransmitters and has potential applications in pharmaceuticals and biochemistry research. Its ability to modulate cellular functions makes it an important molecule in the study of gene expression and regulation, as well as in the development of new drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 96013-00-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,0,1 and 3 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 96013-00:
(7*9)+(6*6)+(5*0)+(4*1)+(3*3)+(2*0)+(1*0)=112
112 % 10 = 2
So 96013-00-2 is a valid CAS Registry Number.
96013-00-2Relevant articles and documents
Synthesis of Nucleoside Triphosphates from 2′-3′-Protected Nucleosides Using Trimetaphosphate
Mohamady, Samy,Taylor, Scott D.
supporting information, p. 580 - 583 (2016/02/18)
Chemists have been attempting to triphosphorylate nucleosides and other alcohols using trimetaphosphate (TriMP) since the 1960s. However, this route appears to have been abandoned due to poor yields. The first practical syntheses of nucleoside triphosphates (NTPs) are reported using TriMP as the key reagent. This was achieved by reacting the tetrabutylammonium salt of TriMP with mesitylenesulfonyl chloride in the presence of DABCO in pyridine followed by the addition of an appropriately protected nucleoside and phthalimide. Quenching the reaction with aqueous buffer followed by hydrolysis of the OH protecting groups gave the NTPs in good yield.
