96035-07-3Relevant articles and documents
Selective Inhibition of an Apicoplastic Aminoacyl-tRNA Synthetase from Plasmodium falciparum
Hoen, Rob,Novoa, Eva Maria,López, Alba,Camacho, Noelia,Cubells, Laia,Vieira, Pedro,Santos, Manuel,Marin-Garcia, Patricia,Bautista, Jose Maria,Cortés, Alfred,Ribas de Pouplana, Lluís,Royo, Miriam
, p. 499 - 509 (2013)
The resistance of malaria parasites to available drugs continues to grow, and this makes the need for new antimalarial therapies pressing. Aminoacyl-tRNA synthetases (ARSs) are essential enzymes and well-established antibacterial targets and so constitute