96219-55-5 Usage
General Description
(S)-2-(2-oxopyrrolidin-1-yl)propanoic acid, also known as pipecolic acid, is a naturally occurring compound that is synthesized in the body from lysine. It is an important intermediate in the biosynthesis of the neurotransmitter gamma-aminobutyric acid (GABA) and plays a significant role in the regulation of the GABAergic system. Pipecolic acid has been investigated for its potential therapeutic applications, particularly in relation to neurological disorders such as epilepsy and schizophrenia. It also exhibits anti-inflammatory and immunomodulatory properties and has been studied for its potential role in autoimmune diseases. Additionally, pipecolic acid has been used as a building block in the synthesis of pharmaceuticals and agrochemicals due to its unique chemical structure and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 96219-55-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,2,1 and 9 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 96219-55:
(7*9)+(6*6)+(5*2)+(4*1)+(3*9)+(2*5)+(1*5)=155
155 % 10 = 5
So 96219-55-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H11NO3/c1-5(7(10)11)8-4-2-3-6(8)9/h5H,2-4H2,1H3,(H,10,11)/t5-/m0/s1
96219-55-5Relevant articles and documents
KetoABNO/NOx Cocatalytic Aerobic Oxidation of Aldehydes to Carboxylic Acids and Access to α-Chiral Carboxylic Acids via Sequential Asymmetric Hydroformylation/Oxidation
Miles, Kelsey C.,Abrams, M. Leigh,Landis, Clark R.,Stahl, Shannon S.
supporting information, p. 3590 - 3593 (2016/08/16)
A method for aerobic oxidation of aldehydes to carboxylic acids has been developed using organic nitroxyl and NOx cocatalysts. KetoABNO (9-azabicyclo[3.3.1]nonan-3-one N-oxyl) and NaNO2 were identified as the optimal nitroxyl and NOx sources, respectively. The mildness of the reaction conditions enables sequential asymmetric hydroformylation of alkenes/aerobic aldehyde oxidation to access α-chiral carboxylic acids without racemization. The scope, utility, and limitations of the oxidation method are further evaluated with a series of achiral aldehydes bearing diverse functional groups.
