96249-79-5

Basic information

• Product Name: 2-Propen-1-one, 1-(6-hydroxy-1,3-benzodioxol-5-yl)-3-phenyl-, (E)-
• CAS NO: 96249-79-5
• Molecular Formula: C16H12O4
• Molecular Weight: 268.269
• Mol File: 96249-79-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1-(6-hydroxy-1,3-benzodioxol-5-yl)-3-phenyl-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-(6-hydroxy-1,3-benzodioxol-5-yl)-3-phenyl-, (E)-(96249-79-5)
• EPA Substance Registry System: 2-Propen-1-one, 1-(6-hydroxy-1,3-benzodioxol-5-yl)-3-phenyl-, (E)-(96249-79-5)

Safety Data

• Hazardous Substances Data: 96249-79-5(Hazardous Substances Data)

Upstream product

• 66003-50-7 1-<4,5-(methylenedioxy)-2-hydroxyphenyl>ethanone 
• 100-52-7 benzaldehyde 
• 326-58-9 acetic acid benzo[1,3]dioxol-5-yl ester 
• 533-31-3 Sesamol 
• 64-17-5 ethanol 
• 102-92-1 Cinnamoyl chloride 
• 857982-72-0 3-hydroxy-1-(6-hydroxy-benzo[1,3]dioxol-5-yl)-3-phenyl-propan-1-one 

Downstream Products

• 4424-13-9 6,7-methylenedioxy-2-phenyl-4H-benzopyran-4-one 

Relevant articles and documents

UNUSUAL FRIEDEL-CRAFTS REACTIONS, IX. ONE-STEP ORTHO-ACYLATION OF PHENOLS WITH α,β-UNSATURATED ACYL CHLORIDES. SYNTHESIS OF 2'-HYDROXYCHALCONES AND SORBICILLIN ANALOGUES

The reaction of bromomagnesium phenolates 1 in toluene with α,β-unsaturated acyl chlorides 2 at room temperature provides a straightforward highly selective synthesis of α,β-unsaturated 2-hydroxyarylketones 3. 2'-Hydroxychalcones, ortho-sorbylphenols including sorbicillin 3g, and ortho-propiolylphenols were usefully synthesized by this way.This reaction provides a further example of the synthetic versatility of the chelation-controlled approach in the elaboration of phenol derivatives.