96249-87-5

Basic information

• Product Name: (2E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride
• Synonyms: (2E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride;2-propenoyl chloride, 3-(1,3-benzodioxol-5-yl)-, (2E)-;3-(1,3-Benzodioxol-5-yl)acryloyl chloride;3-(benzo[d][1,3]dioxol-5-yl)acryloyl chloride
• CAS NO: 96249-87-5
• Molecular Formula: C₁₀H₇ClO₃
• Molecular Weight: 210.62
• Mol File: 96249-87-5.mol
• Article Data: 52

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride(96249-87-5)
• EPA Substance Registry System: (2E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride(96249-87-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 96249-87-5(Hazardous Substances Data)

Upstream product

• 2373-80-0 3,4-methylenedioxy-trans-cinnamic acid 
• 120-57-0 piperonal 
• 2373-80-0 3,4-(methylenedioxy)cinnamic acid 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 120680-81-1 2-((E)-3-Benzo[1,3]dioxol-5-yl-acryloylamino)-3-phenyl-propionic acid 
• 114133-04-9 1-(benzoyloxy)-5-<((E)-piperonylacryloyl)oxy>-1(E),3(E)-pentadiene 
• 124778-00-3 (E)-3-(benzo[d][1,3]dioxol-5-yl)-N,N-dimethylacrylamide 
• 159052-13-8 α-(3,4-methylenedioxycinnamoyl)benzylidene(triphenyl)phosphorane 
• 82857-82-7 (E)-3-(benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)prop-2-en-1-one 
• 356546-38-8 N-[(E)-3,4-methylenedioxycinnamoyl]dopamine 
• 125187-31-7 (E)-3-(benzo[d][1,3]dioxol-5-yl)-N-(3,4-dimethoxyphenethyl)acrylamide 
• 1027046-05-4 3-benzo[1,3]dioxol-5-yl-N-(2-bromo-4-fluoro-phenyl)-acrylamide 
• 75288-96-9 kukoamine A 
• 1333380-14-5 C₄₅H₄₄N₂O₆Si 

Relevant articles and documents

Design, synthesis, and taste evaluation of a high-intensity umami-imparting oxazole-based compound

Umami taste is imparted predominantly by monosodium glutamate (MSG) and 5′-ribonucleotides. Recently, several different classes of hydrophobic umami-imparting compounds, the structures of which are quite different from MSG, have been reported. To obtain a novel umami-imparting compound, N-cinnamoyl phenethylamine was chosen as the lead compound, and a rational structure-optimization study was conducted on the basis of the pharmacophore model of previously reported compounds. The extremely potent umami-imparting compound 2-[[[2-[(1E)-2-(1,3-benzodioxol-5-yl)ethenyl]-4-oxazolyle]methoxy]methyl]pyridine, which exhibits 27,000 times the umami taste of MSG, was found. Its terminal pyridine residue and linear structure are suggested to be responsible for its strong activity. The time taken to reach maximum taste intensity exhibited by it, as determined by the time-intensity method, is 22.0 s, whereas the maximum taste intensity of MSG occurs immediately. This distinct difference in the time-course taste profile may be due to the hydrophobicity and strong receptor affinity of the new compound.

Cinnamyl carboxylate compound and application thereof

The invention discloses a cinnamyl carboxylate compound and application of agriculturally acceptable salt thereof as a herbicide. The compound is shown as a general formula (I), wherein substituent groups in the general formula (I) are defined in the spec

Modular Cyclopentenone Synthesis through the Catalytic Molecular Shuffling of Unsaturated Acid Chlorides and Alkynes

We describe a general strategy for the intermolecular synthesis of polysubstituted cyclopentenones using palladium catalysis. Overall, this reaction is achieved via a molecular shuffling process involving an alkyne, an α,β-unsaturated acid chloride, which serves as both the alkene and carbon monoxide source, and a hydrosilane to create three new C-C bonds. This new carbon monoxide-free pathway delivers the products with excellent yields. Furthermore, the regioselectivity is complementary to conventional methods for cyclopentenone synthesis. In addition, a set of regio- and chemodivergent reactions are presented to emphasize the synthetic potential of this novel strategy.