96255-83-3

Basic information

• Product Name: (R)-2,5,12-Trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-2-carboxylic acid; compound with (1R,2S)-2-dimethylamino-1-phenyl-propan-1-ol
• CAS NO: 96255-83-3
• Molecular Weight: 533.578
• Mol File: 96255-83-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2,5,12-Trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-2-carboxylic acid; compound with (1R,2S)-2-dimethylamino-1-phenyl-propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2,5,12-Trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-2-carboxylic acid; compound with (1R,2S)-2-dimethylamino-1-phenyl-propan-1-ol(96255-83-3)
• EPA Substance Registry System: (R)-2,5,12-Trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-2-carboxylic acid; compound with (1R,2S)-2-dimethylamino-1-phenyl-propan-1-ol(96255-83-3)

Safety Data

• Hazardous Substances Data: 96255-83-3(Hazardous Substances Data)

Upstream product

• 96292-36-3 (+/-)-2-cyano-2,5,12-trihydroxy-1,2,3,4-tetrahydro-6,11-naphthacenedione 
• 58977-09-6 5,12-dihydroxy-1,2,3,4-tetrahydro-2,6,11-naphthacenetrione 
• 552-79-4 (-)-N-methylephedrine 
• 96292-37-4 (+/-)-2,5,12-trihydroxy-6,11-dioxo-1,2,3,4-tetrahydro-2-naphthacenecarboxylic acid 

Relevant articles and documents

A SIMPLE EFFICIENT SYNTHESIS OF KEY SYNTHETIC INTERMEDIATES OF 4-DEMETHOXYANTHRACYCLINONES, (+/-)- AND (R)-(-)-7-DEOXY-4-DEMETHOXYDAUNOMYCINONE

(+/-)-2,5,12-Trihydroxy-1,2,3,4-tetrahydronaphthacene-6,11-di-one-2-carboxylic acid was found to readily afford the racemic title compound by successive treatments with N,N'-carbonyldiimidazole and methylmagnesium bromide in the presence of trimethylsilyl triflate.The same reaction scheme could also furnish the optically pure title compound from the (R)-carboxylic acid produced by the optical resolution.