96287-28-4 Usage
Description
(S)-Azetidine-2-carboxylic acid ethyl ester hydrochloride is a chemical compound that serves as an ester derivative of (S)-azetidine-2-carboxylic acid, a crucial building block in the synthesis of pharmaceuticals and agrochemicals. Its hydrochloride form enhances stability and ease of handling in laboratory settings, making it a valuable asset in the production of various drugs and agricultural products.
Uses
Used in Pharmaceutical Industry:
(S)-Azetidine-2-carboxylic acid ethyl ester hydrochloride is used as a chiral intermediate for the synthesis of bioactive molecules, playing a pivotal role in the development of new drugs with improved efficacy and selectivity.
Used in Agricultural Industry:
In the agrochemical sector, (S)-Azetidine-2-carboxylic acid ethyl ester hydrochloride is utilized as a key component in the production of effective and targeted agricultural products, contributing to enhanced crop protection and yield.
Check Digit Verification of cas no
The CAS Registry Mumber 96287-28-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,2,8 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 96287-28:
(7*9)+(6*6)+(5*2)+(4*8)+(3*7)+(2*2)+(1*8)=174
174 % 10 = 4
So 96287-28-4 is a valid CAS Registry Number.
96287-28-4Relevant articles and documents
Biocatalytic One-Carbon Ring Expansion of Aziridines to Azetidines via a Highly Enantioselective [1,2]-Stevens Rearrangement
Miller, David C.,Lal, Ravi G.,Marchetti, Luca A.,Arnold, Frances H.
supporting information, p. 4739 - 4745 (2022/03/27)
We report enantioselective one-carbon ring expansion of aziridines to make azetidines as a new-to-nature activity of engineered "carbene transferase" enzymes. A laboratory-evolved variant of cytochrome P450BM3, P411-AzetS, not only exerts unparalleled stereocontrol (99:1 er) over a [1,2]-Stevens rearrangement but also overrides the inherent reactivity of aziridinium ylides, cheletropic extrusion of olefins, to perform a [1,2]-Stevens rearrangement. By controlling the fate of the highly reactive aziridinium ylide intermediates, these evolvable biocatalysts promote a transformation which cannot currently be performed using other catalyst classes.