96303-88-7 Usage
Description
(+)-N,N-Dicyclohexyl-(1R)-isoborneol-10-sulfonamide is a chiral sulfonamide compound characterized by its white solid form, high melting point, and low solubility in water. It is recognized for its utility in chromatography as a chiral stationary phase and in asymmetric synthesis as a resolving agent. (+)-N,N-DICYCLOHEXYL-(1R)-ISOBORNEOL-10-SULFONAMIDE's ability to form stable complexes with various metal ions extends its applications to metal ion separations and detection. Furthermore, it has been investigated for potential antimicrobial and antimalarial properties, showcasing its versatility in scientific and medical research.
Uses
Used in Chromatography Industry:
(+)-N,N-Dicyclohexyl-(1R)-isoborneol-10-sulfonamide is used as a chiral stationary phase for the separation of enantiomers in chromatographic processes. Its high melting point and low water solubility make it particularly suitable for high-temperature separations, enhancing the efficiency and selectivity of enantiomeric resolution.
Used in Asymmetric Synthesis:
In the field of asymmetric synthesis, (+)-N,N-Dicyclohexyl-(1R)-isoborneol-10-sulfonamide serves as a resolving agent, facilitating the production of enantiomerically pure compounds. This is crucial for the synthesis of pharmaceuticals and agrochemicals where the desired biological activity is often associated with a specific enantiomer.
Used in Metal Ion Separation and Detection:
(+)-N,N-Dicyclohexyl-(1R)-isoborneol-10-sulfonamide is utilized for its metal ion complexing properties in applications involving metal ion separations and detection. Its capacity to form stable complexes with metal ions is valuable in analytical chemistry for the precise identification and quantification of metal content in various samples.
Used in Antimicrobial and Antimalarial Research:
(+)-N,N-DICYCLOHEXYL-(1R)-ISOBORNEOL-10-SULFONAMIDE is explored for its potential as an antimicrobial and antimalarial agent, indicating its use in the development of new therapeutics to combat resistant strains of bacteria and parasites, respectively. This research avenue could lead to innovative treatments in the fields of infectious diseases and tropical medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 96303-88-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,3,0 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 96303-88:
(7*9)+(6*6)+(5*3)+(4*0)+(3*3)+(2*8)+(1*8)=147
147 % 10 = 7
So 96303-88-7 is a valid CAS Registry Number.
InChI:InChI=1/C22H39NO3S/c1-21(2)17-13-14-22(21,20(24)15-17)16-27(25,26)23(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h17-20,24H,3-16H2,1-2H3/t17-,20-,22-/m0/s1
96303-88-7Relevant articles and documents
Application in asymmetric Morita-Baylis-Hillman reactions
McIteka, Lulama P.,Lobb, Kevin A.,Kaye, Perry T.
, p. 151 - 163 (2016/10/22)
N-Substituted 2-exo-hydroxybornyl-10-sulfonamides, prepared as potential chiral auxiliaries for use in asymmetric Morita-Baylis-Hillman (MBH) reactions, have been treated with acryloyl chloride to afford the corresponding 2-exo-Acrylate esters as MBH subs
Synthesis of new fluorine-containing taxoids by means of β-lactam synthon method
Ojima,Kuduk,Slater,Gimi,Sun
, p. 209 - 224 (2007/10/02)
A series of new fluorine-containing analogs of paclitaxel and docetaxel are synthesized using the coupling of (3R,4S)-1-acyl-β-lactams with high enantiomeric purity with properly protected baccatin III, 10-deacetylbaccatin III, and 14β-hydroxy-10-deacetyl
Chiral acrylates as substrates in Baylis-Hillman reaction
Basavaiah,Gowriswari,Sarma,Dharma Rao
, p. 1621 - 1624 (2007/10/02)
DABCO induces diastereoselective (7-70%) coupling of chiral acrylates (1-3) with aldehydes to produce the corresponding 2-(1-hydroxyalkyl)acrylates.