96402-49-2 Usage
Description
(S)-N-Fmoc-1-Naphthylalanine, also known as Fmoc-1-Nal-OH, is an amino acid derivative characterized by its white to beige powder form. It is a chiral compound with the (S) configuration and is widely used in chemical synthesis and peptide chemistry due to its unique properties.
Uses
Used in Chemical Synthesis:
(S)-N-Fmoc-1-Naphthylalanine is used as a building block in chemical synthesis for the creation of complex organic molecules. Its naphthyl group provides unique structural and electronic properties that can be exploited in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Peptide Chemistry:
In peptide chemistry, (S)-N-Fmoc-1-Naphthylalanine is used as a non-natural amino acid for the synthesis of modified peptides and proteins. Its incorporation into peptide sequences can alter the properties of the resulting molecules, such as stability, solubility, and biological activity, making it a valuable tool for the development of novel therapeutic agents and diagnostic tools.
Used in Drug Discovery:
(S)-N-Fmoc-1-Naphthylalanine is used as a key component in drug discovery for the design and synthesis of new pharmaceutical compounds. Its unique structural features can be leveraged to develop molecules with improved binding affinity, selectivity, and pharmacokinetic properties, contributing to the advancement of innovative drug candidates.
Used in Materials Science:
In materials science, (S)-N-Fmoc-1-Naphthylalanine can be used as a functional monomer for the synthesis of novel polymers and materials with tailored properties. Its naphthyl group can impart specific characteristics, such as fluorescence, self-assembly, or molecular recognition, which can be harnessed for applications in sensors, imaging, or nanotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 96402-49-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,4,0 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 96402-49:
(7*9)+(6*6)+(5*4)+(4*0)+(3*2)+(2*4)+(1*9)=142
142 % 10 = 2
So 96402-49-2 is a valid CAS Registry Number.
InChI:InChI=1/C28H23NO4/c30-27(31)26(16-19-10-7-9-18-8-1-2-11-20(18)19)29-28(32)33-17-25-23-14-5-3-12-21(23)22-13-4-6-15-24(22)25/h1-15,25-26H,16-17H2,(H,29,32)(H,30,31)/p-1/t26-/m0/s1
96402-49-2Relevant articles and documents
Cyclic peptides as selective tachykinin antagonists
Williams,Curtis,McKnight,Maguire,Young,Veber,Baker
, p. 2 - 10 (2007/10/02)
Twenty homodetic cyclic peptides based on the C-terminal sequence of substance P were prepared (Table I) by a combination of solid-phase techniques and cyclizations using azide coupling procedures. Incorporation of dipeptide mimics based on substituted γ-