96548-91-3

Basic information

• Product Name: 4-Pyrimidinamine, 2-fluoro- (9CI)
• Synonyms: 4-Pyrimidinamine, 2-fluoro- (9CI);2-fluoropyrimidin-4-amine
• CAS NO: 96548-91-3
• Molecular Formula: C₄H₄FN₃
• Molecular Weight: 113.0930632
• Product Categories: PYRIMIDINE
• Mol File: 96548-91-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 324.9±34.0 °C(Predicted)
• Appearance: /
• Density: 1.372±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 2.58±0.10(Predicted)
• CAS DataBase Reference: 4-Pyrimidinamine, 2-fluoro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyrimidinamine, 2-fluoro- (9CI)(96548-91-3)
• EPA Substance Registry System: 4-Pyrimidinamine, 2-fluoro- (9CI)(96548-91-3)

Safety Data

• Hazardous Substances Data: 96548-91-3(Hazardous Substances Data)

Usage

Description

4-Pyrimidinamine, 2-fluoro(9CI) is a chemical compound with the molecular formula C4H3FN4. It is a derivative of pyrimidine with a fluorine atom attached at the 2 position. 4-Pyrimidinamine, 2-fluoro(9CI) is of interest to researchers due to its potential applications in various fields, particularly in the pharmaceutical and agrochemical industries.

Uses

Used in Pharmaceutical Industry:
4-Pyrimidinamine, 2-fluoro(9CI) is used as a building block for the synthesis of various biologically active molecules. Its unique structure and fluorinated nature contribute to the development of new drugs with improved properties, such as enhanced bioavailability, selectivity, and potency.
Used in Agrochemical Industry:
In the agrochemical field, 4-Pyrimidinamine, 2-fluoro(9CI) serves as a key intermediate in the synthesis of agrochemicals with potential pesticidal or herbicidal activities. Its incorporation into these molecules can lead to the development of more effective and environmentally friendly products.
Used in Fluorine Chemistry Research:
4-Pyrimidinamine, 2-fluoro(9CI) is also used as a valuable tool in the study of fluorine chemistry. Its presence in various molecular structures allows researchers to explore the effects of fluorination on the properties and reactivity of compounds, which can be crucial in drug design and development.

Upstream product

• 2802-61-1 2,4-difluoropyrimidine 

Downstream Products

• 881207-82-5 ethyl 4-(2-fluoropyrimidin-4-ylamino)-2-phenylpyrimidine-5-carboxylate 

Relevant articles and documents

Peptide deformylase inhibitors

The present invention relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, corresponding pharmaceutical compositions, compound preparation and treatment methods directed to bacterial infections and inhibition of bacterial peptide deformylase (PDF) activity.

SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE

The present invention relates to pyridines, pyrimidines and derivatives thereof, and pharmaceutically acceptable salts thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic beta cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.