96681-85-5

Basic information

• Product Name: 3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid
• Synonyms: 3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid;3-(2-Carboxyethyl)-2,5-bis(2-hydroxyethyl)pyrazine;3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid Discontinued;Clavulanate Potassium EP Impurity B;Potassium Clavulanate impurity B;3-(3,6-bis(2-hydroxyethyl)pyrazin-2-yl)propanoic acid
• CAS NO: 96681-85-5
• Molecular Formula: C11H16N2O4
• Molecular Weight: 240
• Product Categories: Aromatics;Heterocycless;Impurities
• Mol File: 96681-85-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 451.3±40.0 °C(Predicted)
• Appearance: /
• Density: 1.331±0.06 g/cm3(Predicted)
• PKA: 4.19±0.10(Predicted)
• CAS DataBase Reference: 3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid(96681-85-5)
• EPA Substance Registry System: 3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid(96681-85-5)

Safety Data

• Hazardous Substances Data: 96681-85-5(Hazardous Substances Data)

Usage

Description

3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid is an organic compound that serves as an impurity in Clavulanic acid, a β-lactam antibiotic. It is formed during the decomposition of Clavulanic acid and can also catalyze its decomposition, along with other decomposition products.

Uses

Used in Pharmaceutical Industry:
3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid is used as an impurity in Clavulanic acid for its role in the decomposition process. Understanding and controlling the presence of this impurity is crucial for maintaining the stability and efficacy of Clavulanic acid as a β-lactam antibiotic in medical treatments.

Upstream product

• 61177-45-5 potassium clavulanate 

Relevant articles and documents

Degradation of clavulanic acid in aqueous alkaline solution: Isolation and structural investigation of degradation products

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