96690-02-7

Basic information

• Product Name: 5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose
• Synonyms: 5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose
• CAS NO: 96690-02-7
• Molecular Weight: 428.601
• Mol File: 96690-02-7.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: 5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose(96690-02-7)
• EPA Substance Registry System: 5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose(96690-02-7)

Safety Data

• Hazardous Substances Data: 96690-02-7(Hazardous Substances Data)

Upstream product

• 532-20-7 D-Ribose 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 67814-68-0 2,3-O-isopropylidene-β-D-ribofuranose 
• 67814-68-0 2,3-O-isopropylidene-D-ribofuranose 
• 50-69-1 D-ribose 
• 10257-32-6 D-ribose 
• 13199-25-2 2,3-O-Isopropylidene-D-ribose 

Downstream Products

• 557794-46-4 5-(tert-butyldiphenylsilyl)-1-deoxy-1-hydroxyamino-2,3-O-isopropylidene-β-D-ribo-1,4-pentofuranose 
• 254114-36-8 Bromo-[(3aR,4R,6R,6aR)-6-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-acetaldehyde 
• 254114-44-8 3-(5'-O-tert-Butyldiphenylsilyl-2',3'-O-isopropylidene-β-D-ribofuranosyl)-6-(methylsulfanyl)imidazo[2,1-f][1,2,4]triazine 
• 254114-42-6 3-(5'-O-tert-Butyldiphenylsilyl-2',3'-O-isopropylidene-β-D-ribofuranosyl)-6,8-bis(methylsulfanyl)imidazo[2,1-f][1,2,4]triazine 
• 254114-43-7 3-(5'-O-tert-Butyldiphenylsilyl-2',3'-O-isopropylidene-β-D-ribofuranosyl)-8-hydrazino-6-(methylsulfanyl)imidazo[2,1-f][1,2,4]triazine 
• 915694-38-1 (3aR,3bR,4aS,5S,5aS)-3b-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethylhexahydrocyclopropa[3,4]cyclopenta[1,2-d][1,3]dioxol-5-ol 
• 82950-51-4 3-(5-O-tert-butyldiphenylsilyl-2,3-O-isopropylidene-α-D-ribofuranosyl)prop-1-ene 
• 130222-85-4 5-O-tert-butyldiphenylsilyl-2,3-O-isopropylidene-D-ribitol 

Relevant articles and documents

Stereoselective synthesis of selenium-containing glycoconjugates via the mitsunobu reaction

A simple and efficient route for the synthesis of new glycoconjugates has been developed. The approach acts as a model for a mini-library of compounds with a deoxy-selenosugar core joined to a polyphenolic moiety with well-known antioxidant properties. An unexpected stereocontrol detected in the Mitsunobu key reaction led to the most attractive product showing a natural Dconfiguration. Thus, we were able to obtain the target molecules from the commercially available D-ribose via a shorter and convenient sequence of reactions.

Highly regioselective and stereoselective synthesis of C-Aryl glycosidesvianickel-catalyzedortho-C-H glycosylation of 8-aminoquinoline benzamides

C-Aryl glycosides are of high value as drug candidates. Here a novel and cost-effective nickel catalyzedortho-CAr-H glycosylation reaction with high regioselectivity and excellent α-selectivity is described. This method shows great functional group compatibility with various glycosides, showing its synthetic potential. Mechanistic studies indicate that C-H activation could be the rate-determining step.

DERIVATIVES OF GLYCERO-MANNO-HEPTOSE ADP FOR USE IN MODULATING IMMUNE RESPONSE

The disclosure provides compounds, compositions and methods related to activating alpha-kinase 1 (ALPK1) for modulating an immune response and treating or preventing cancer, infection, inflammation and related diseases and disorders as well as potentiating an immune response to a target antigen. The disclosure also provides heterocyclic compounds of formula (I) as agonists of alpha protein kinase 1 (ALPK1) and their use in activating ALPK1, modulating an immune response and treating diseases such as cancer, wherein A1, A2, L1, L2, L3, Z1, Z2, W1, W2, R1, R2, R3, R4, R5, R6 and R7 are as defined herein.