96841-76-8Relevant articles and documents
A NEW ALKYLAMIDATION REACTION. REGIOSPECIFIC CONDENSATION OF CARBANIONS ON CYCLO 1,3-OXOIMMINIUM SALTS
Dreme, M.,Brunel, S.,Perchec, P. Le,Garapon, J.,Sillion, B.
, p. 4947 - 4954 (2007/10/02)
Cyclo 1,3-oxoimminium salts are found to react regiospecifically with functional carbanions.Steric effects induced at the C-2 site on salts or at the carbanionic centers promote the condensation at the C-5 or C-6 opposite sites.A bulky substituent such as 2-mesityl group is a powerful auxiliary which not only modifies the steric environment at the reactive C-2 site but also contributes to enhance the reactivity of the cyclo oxoimminium ring.
