96853-36-0

Basic information

• Product Name: β-(2-hydroxyphenyl)nitroethane
• Synonyms: β-(2-hydroxyphenyl)nitroethane
• CAS NO: 96853-36-0
• Molecular Weight: 167.164
• Mol File: 96853-36-0.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: β-(2-hydroxyphenyl)nitroethane(CAS DataBase Reference)
• NIST Chemistry Reference: β-(2-hydroxyphenyl)nitroethane(96853-36-0)
• EPA Substance Registry System: β-(2-hydroxyphenyl)nitroethane(96853-36-0)

Safety Data

• Hazardous Substances Data: 96853-36-0(Hazardous Substances Data)

Upstream product

• 3156-43-2 2-(2-nitro-vinyl)-phenol 
• 90-02-8 salicylaldehyde 
• 28448-04-6 3-nitrocoumarin 
• 89-95-2 2-methyl-benzyl alcohol 
• 622396-69-4 3,4-dihydro-3-nitrochromen-2-one 
• 3156-43-2 2-[(E)-2-nitrovinyl]phenol 

Downstream Products

• 1438253-56-5 (Z)-2-(2-hydroxyphenyl)acetaldehyde oxime 
• 1438253-42-9 (E)-2-(2-hydroxyphenyl)acetaldehyde oxime 

Relevant articles and documents

Iridium-catalyzed highly chemoselective and efficient reduction of nitroalkenes to nitroalkanes in water

An iridium-catalyzed highly chemoselective and efficient transfer hydrogenation reduction of structurally diverse nitroalkenes was realized at very low catalyst loading (S/C = up to 10000 or 20?000), using formic acid or sodium formate as a traceless hydride donor in water. Excellent functionality tolerance is also observed. The turnover number and turnover frequency of the catalyst reach as high as 18?600 and 19?200 h-1, respectively. An inert atmosphere protection is not required. The reactivities of nitroalkenes are dependent on their substitution pattern, and the pH value is a key factor to accomplish the complete conversion and excellent chemoselectivity. Purification of products is achieved by simple extraction without column chromatography. The reduction procedure is facilely amplified to 10 g scale at 10?000 S/C ratio. The potential of this green reduction in enantioselective hydrogenation has been demonstrated.

Asymmetric dearomatization of 2-nitrobenzofurans by organocatalyzed one-step Michael addition to access 3,3′-disubstituted oxindoles

An efficient enantioselective dearomatization of 2-nitrobenzofurans was realized via an organocatalyzed one-step Michael addition process. This method provides a facile strategy to access a range of structurally diverse 3,3′-disubstituted oxindoles, which feature an intriguing combination of two privileged motifs including 3-pyrrolyl-substituted-oxindoles and 2,3-dihydrobenzofurans substructures, in excellent results.

Enantioselective dearomative [3+2] cycloaddition of 2-nitrobenzofurans with aldehyde-derived Morita-Baylis-Hillman carbonates

The phosphine-catalyzed asymmetric dearomative [3+2] cycloaddition of 2-nitrobenzofurans with aldehyde-derived Morita-Baylis-Hillman (MBH) carbonates or allenoate was developed. The reaction with MBH carbonates resulted in a series of cyclopentabenzofurans containing three contiguous stereocenters with good to high yields, diastereoselectivities and enantioselectivities. The use of allenoate also gave the target product with moderate enantioselectivity.