97-04-1 Usage
Description
2-CHLORO-5-SULFAMOYLBENZOIC ACID is an organic compound characterized by the presence of a chloro and sulfamoyl group attached to a benzoic acid structure. It is a beige solid with potential applications in various fields, particularly in organic synthesis.
Uses
Used in Organic Synthesis:
2-CHLORO-5-SULFAMOYLBENZOIC ACID is used as a synthetic intermediate for the production of various pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure allows for the formation of diverse chemical entities through further reactions and modifications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-CHLORO-5-SULFAMOYLBENZOIC ACID is used as a building block for the development of new drugs. Its chemical properties enable the creation of novel compounds with potential therapeutic applications, contributing to the advancement of medicine.
Used in Agrochemical Industry:
2-CHLORO-5-SULFAMOYLBENZOIC ACID is also utilized in the agrochemical industry for the synthesis of active ingredients in pesticides and herbicides. Its incorporation into these products can lead to improved efficacy and selectivity, benefiting agricultural practices.
Used in Specialty Chemicals:
In the specialty chemicals sector, 2-CHLORO-5-SULFAMOYLBENZOIC ACID is employed as a key component in the synthesis of various high-value compounds. Its versatility in chemical reactions allows for the production of unique specialty chemicals with specific applications in industries such as coatings, dyes, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 97-04-1 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 7 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 97-04:
(4*9)+(3*7)+(2*0)+(1*4)=61
61 % 10 = 1
So 97-04-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H6ClNO4S/c8-6-2-1-4(14(9,12)13)3-5(6)7(10)11/h1-3H,(H,10,11)(H2,9,12,13)/p-1
97-04-1Relevant articles and documents
Novel 4,4-disubstituted piperidine-based C-C chemokine receptor-5 inhibitors with high potency against human immunodeficiency virus-1 and an improved human ether-a-go-go related gene (hERG) profile
Kazmierski, Wieslaw M.,Anderson, Don L.,Aquino, Christopher,Chauder, Brian A.,Duan, Maosheng,Ferris, Robert,Kenakin, Terrence,Koble, Cecilia S.,Lang, Dan G.,Mcintyre, Maggie S,Peckham, Jennifer,Watson, Christian,Wheelan, Pat,Spaltenstein, Andrew,Wire, Mary B.,Svolto, Angilique,Youngman, Michael
scheme or table, p. 3756 - 3767 (2011/07/30)
We recently described (J. Med. Chem. 2008, 51, 6538-6546) a novel class of CCR5 antagonists with strong anti-HIV potency. Herein, we detail SAR converting leads 1 and 2 to druglike molecules. The pivotal structural motif enabling this transition was the secondary sulfonamide substituent. Further finetuning of the substituent pattern in the sulfonamide paved the way to enhancing potency and bioavailability and minimizing hERG inhibition, resulting in discovery of clinical compound 122 (GSK163929).
7-MEMBERED RING COMPOUND, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF
-
Page/Page column 40-41, (2008/06/13)
A 7-membered heterocyclic compound having the formula (I), or its salt, or a solvate thereof with a chymase inhibitory action and useful for the prevention or treatment of various diseases, in which chymase is involved: a method for producing the same, and a pharmaceutical composition useful for the prevention or treatment of diseases, in which chymase is involved, including the compound of having the formula (I), or its pharmaceutically acceptable salt, or a solvate thereof are provided.
Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents
-
, (2008/06/13)
Intermediates for preparing benzylthio-, benzylsulfinyl-, and benzylsylfonyl-benzoic acids, and method of lowering the blood lipid level in mammals employing said acids.
