97022-62-3Relevant articles and documents
Cyclic nucleotide-gated channel block by hydrolysis-resistant tetracaine derivatives
Andrade, Adriana L.,Melich, Kenneth,Whatley, G. Gregory,Kirk, Sarah R.,Karpen, Jeffrey W.
, p. 4904 - 4912 (2011)
To meet a pressing need for better cyclic nucleotide-gated (CNG) channel antagonists, we have increased the biological stability of tetracaine-based blockers by synthesizing amide and thioamide linkage substitutions of tetracaine (1) and a higher affinity