97166-64-8

Basic information

• Product Name: N-Butyl-phthalamic acid ethyl ester
• Synonyms: N-Butyl-phthalamic acid ethyl ester
• CAS NO: 97166-64-8
• Molecular Weight: 249.31
• Mol File: 97166-64-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-Butyl-phthalamic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Butyl-phthalamic acid ethyl ester(97166-64-8)
• EPA Substance Registry System: N-Butyl-phthalamic acid ethyl ester(97166-64-8)

Safety Data

• Hazardous Substances Data: 97166-64-8(Hazardous Substances Data)

Upstream product

• 88-95-9 Phthaloyl dichloride 
• 2306-33-4 monoethyl phthalate 
• 109-73-9 N-butylamine 
• 64-17-5 ethanol 
• 80991-83-9 N-butylisophthalimide 

Downstream Products

• 1515-72-6 N-butylphthalimide 

Relevant articles and documents

A mild, selective, PyBOP mediated procedure for the conversion of primary Amines into phthalimides

A new method for the protection of primary amines or amino alcohols as phthalimides is described. The phthaloyl group is selectively introduced under mild, anhydrous conditions by reacting the amine with 2- (ethoxycarbonyl)benzoic acid activated by PyBOP, followed by the thermally induced cyclization of the resulting phthalamic ester. These reaction conditions are applicable to a variety of primary amines and good yields are obtained in all cases.