97188-29-9

Basic information

• Product Name: 1H-Pyrrole, 3-(4-methylbenzoyl)-1-(phenylsulfonyl)-
• CAS NO: 97188-29-9
• Molecular Formula: C18H15NO3S
• Molecular Weight: 325.388
• Mol File: 97188-29-9.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole, 3-(4-methylbenzoyl)-1-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole, 3-(4-methylbenzoyl)-1-(phenylsulfonyl)-(97188-29-9)
• EPA Substance Registry System: 1H-Pyrrole, 3-(4-methylbenzoyl)-1-(phenylsulfonyl)-(97188-29-9)

Safety Data

• Hazardous Substances Data: 97188-29-9(Hazardous Substances Data)

Upstream product

• 16851-82-4 N-phenylsulfonylpyrrole 
• 874-60-2 4-methyl-benzoyl chloride 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 147089-00-7 (5-Benzoyl-1H-pyrrol-3-yl)-p-tolyl-methanone 
• 147089-01-8 (5-Cyclohexanecarbonyl-1H-pyrrol-3-yl)-p-tolyl-methanone 
• 147088-90-2 2,4-bis(p-methyl)benzoylpyrrole 
• 147089-25-6 3-(2-p-Tolyl-benzo[1,3]dithiol-2-yl)-1H-pyrrole 
• 147089-15-4 [5-(2-Phenyl-benzo[1,3]dithiol-2-yl)-1H-pyrrol-3-yl]-p-tolyl-methanone 
• 147089-51-8 Cyclohexyl-[4-(2-p-tolyl-benzo[1,3]dithiol-2-yl)-1H-pyrrol-2-yl]-methanone 
• 147089-07-4 p-Tolyl-[5-(2-p-tolyl-benzo[1,3]dithiol-2-yl)-1H-pyrrol-3-yl]-methanone 
• 147089-43-8 p-Tolyl-[4-(2-p-tolyl-benzo[1,3]dithiol-2-yl)-1H-pyrrol-2-yl]-methanone 
• 147089-33-6 4-(2-p-Tolyl-benzo[1,3]dithiol-2-yl)-2-(2-p-tolyl-benzo[1,3]oxathiol-2-yl)-1H-pyrrole 
• 147089-54-1 2,4-Bis-(2-p-tolyl-benzo[1,3]dithiol-2-yl)-1H-pyrrole 
• 147089-41-6 2-(2-Cyclohexyl-benzo[1,3]oxathiol-2-yl)-4-(2-p-tolyl-benzo[1,3]dithiol-2-yl)-1H-pyrrole 
• 156026-92-5 3-(Imidazol-1-yl-p-tolyl-methyl)-1'H-[1,3']bipyrrolyl-4'-carboxylic acid ethyl ester 
• 156026-96-9 3-(Imidazol-1-yl-p-tolyl-methyl)-1'H-[1,3']bipyrrolyl-4'-carboxylic acid 
• 156026-88-9 (E)-3-[3-(Imidazol-1-yl-p-tolyl-methyl)-pyrrol-1-yl]-acrylic acid ethyl ester 

Relevant articles and documents

Synthesis of three asymmetric N-confused tetraarylporphyrins

Two monosubstituted and one tetrasubstituted N-confused porphyrins (1-3) were prepared in ca. 3-5% yields using a [2 + 2] synthesis. The monosubstituted porphyrins have carbomethoxy (1) or nitro (2) substituents on one of the meso-phenyl groups, while the meso-phenyl groups of the third NCP (3) are substituted with nitro, bromo, and methyl groups in an AB2C pattern. The specific regiochemistry of the aryl rings around the macrocycle in each porphyrin was definitively determined using a combination of 1D (1H and 13C) and 2D (gHMBC, gHSQC and ROESY) NMR spectroscopy. The absorption spectra of 1-3 in CH2Cl2 are similar to those of N-confused tetraphenylporphyrin (NCTPP) but have Soret and Q bands that are shifted to lower energies with smaller extinction coefficients in comparison to those for NCTPP.

NOVEL HETEROARYL DERIVATIVE

A compound of the following formula (1), or its prodrug or pharmaceutically acceptable salt thereof, being useful as a diabetic medicine or preventive, or blood sugar regulator, or therapeutic agent for hyperlipemia, etc. wherein the ring Z is an optionally substituted heteroaryl, W4 is a single bond, lower alkylene, etc., Ar2 is an optionally substituted aryl, etc., W3 is a single bond, lower alkylene, etc., Ar1 is an optionally substituted arylene, etc., each of W1 and W2 is an optionally substituted lower alkylene, etc., and R1 is carboxyl, an alkoxycarbonyl.

NOVEL HETEROARYL DERIVATIVE

A heteroaryl derivative of the formula (1): (wherein Ring Z is an optionally substituted heteroaryl, R1 is a carboxyl group or an alkoxycarbonyl group, etc., W1 and W2 are an optionally substituted lower alkylene, Ar1 is an optionally substituted arylene or an optionally substituted heteroarylene, W3 is a single bond, a lower alkylene, a lower alkenylene, etc., W4 is a single bond, -NR10-, etc., Ar2 is an optionally substituted aryl or an optionally substituted heteroaryl), or a prodrug thereof, or a pharmaceutically acceptable salt thereof.