97195-92-1

Basic information

• Product Name: 4-Pyridinecarboxylic acid, 2-[[(4-methoxyphenyl)amino]thioxomethyl]hydrazide
• CAS NO: 97195-92-1
• Molecular Formula: C14H14N4O2S
• Molecular Weight: 302.357
• Mol File: 97195-92-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 4-Pyridinecarboxylic acid, 2-[[(4-methoxyphenyl)amino]thioxomethyl]hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinecarboxylic acid, 2-[[(4-methoxyphenyl)amino]thioxomethyl]hydrazide(97195-92-1)
• EPA Substance Registry System: 4-Pyridinecarboxylic acid, 2-[[(4-methoxyphenyl)amino]thioxomethyl]hydrazide(97195-92-1)

Safety Data

• Hazardous Substances Data: 97195-92-1(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 15866-98-5 ammonium salt of N-p-anisylamino dithiocarbamic acid 
• 75-15-0 carbon disulfide 
• 54-85-3 isoniazid 
• 2284-20-0 4-Methoxyphenyl isothiocyanate 

Downstream Products

• 109220-26-0 4-(4-methoxyphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol 
• 109220-26-0 4-(4-methoxyphenyl)-3-(pyridin-4-yl)-5-sulfanylidene-4,5-dihydro-1H-1,2,4-triazole 
• 118222-46-1 C₁₅H₁₄N₄OS 
• 1257542-96-3 C₁₅H₁₄N₄O₃S 
• 106271-19-6 N-(4-methoxyphenyl)-5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine 
• 117080-55-4 N-(4-methoxyphenyl)-5-(pyridin-4-yl)-1,3,4-oxadiazol-2-amine 

Relevant articles and documents

Synthesis, molecular docking, and evaluation of antibacterial activity of 1,2,4-triazole-norfloxacin hybrids

A series of 1,2,4-triazole-norfloxacin hybrids was designed, synthesized, and evaluated for in vitro antibacterial activity against common pathogens. All the newly synthesized compounds were characterized by Fourier-transform infrared spectrophotometry, p

Synthesis and antimicrobial activity of some new 1,2,4-trizoles

A series of 1,2,4-triazole derivatives were synthesized using appropriate synthetic route and structures were confirmed by IR,1H NMR and elemental analysis. All the synthesized compounds (6a-6h and 7a-7h) were evaluated for antimicrobial activity by determining their minimum inhibitory concentrations (MICs) against a panel of Gram-positive, Gram-negative bacteria and fungi. Most of the compounds showed significant antimicrobial activity against Gram-positive bacteria viz. S. aureus, B. subtilis, Gram-negative bacteria viz. E. coli, P. aerugenosa and fungi viz. C. albicans, A. niger. Some of the compounds showed better antibacterial activities against Gram-positive bacteria compared to Gram-negative bacteria. Compounds 7g, 6g, 6a exhibited good MICs against Gram-positive bacteria and 7f showed better MICs against Gram-negative bacteria compared to reference norfloxacin. Compounds 7f and 7d exhibited MICs which is equipotent to the reference drug ketoconazole.

Synthesis and antitumor activity of 4-cyclohexyl/aryl-5-(pyridin-4-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thiones

The reaction of 2-isonicotinoyl-N-cyclohexyl/arylhydrazinecarbothioamide (2a-r) with sodium hydroxide, in each case, a single product was obtained. The structures of the compounds were confirmed on the basis of their elemental analysis and spectral data.