97332-54-2Relevant articles and documents
On the cis-Effect of Radical Addition Reactions at Alkenes
Giese, Bernd,Lachhein, Stephen
, p. 1616 - 1620 (2007/10/02)
The trans-alkenes 2e - h react faster with cyclohexyl radicals than the cis-alkenes 3e - h (Table 1).Radical addition reactions at alkylidenemalonic esters 1 show that this cis-effect increases with the bulkyness of the substituents (Table 1).However, the difference in the reactivity between trans- and cis-alkenes exerts no effect on the regioselectivity (Table 3).It is concluded that the reason for the cis-effect is a twisting of the ?-system that influences the reactivity of both vinylic C-atoms to the same extent.
