97512-83-9Relevant articles and documents
SOME OBSERVATION CONCERNING THE S-NITROSO AND S-PHENYLSULPHONYL DERIVATIES OF L-CYSTEINE AND GLUTATHIONE
Hart, Terance W.
, p. 2013 - 2016 (1985)
The preparation of the thiolsulphonate derivatives 3 and 7 of L-cysteine and glutathione, respectively, via their corresponding S-nitroso derivatives 2 and 6, is described.
Exploring new activating groups for reactive cysteine NCAs
Huesmann, David,Sch?fer, Olga,Braun, Lydia,Klinker, Kristina,Reuter, Thomas,Barz, Matthias
, p. 1138 - 1142 (2016/03/09)
Due to its ability to reversibly crosslink proteins, cysteine has a unique role as an amino acid in nature. For controlled, asymmetric formation of disulfides from two thiols, one thiol needs to be activated. While few activating groups for cysteine have been proposed, they are usually not stable against amines making them unsuitable for solid phase peptide synthesis or amine initiated polymerization of α-amino acid-N-carboxy-anhydrides (NCAs). In this Letter we describe a series of new thiol activated cysteines, as well as their NCAs and explore the link between electron deficiency of the leaving group and control over NCA polymerization.
Thiosulphonate derivatives of amino acids
Hart,Vine,Walden
, p. 3879 - 3882 (2007/10/02)
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