97614-42-1

Basic information

• Product Name: 2-(1'-Imidazoylsulfonyl)-1,3,5-tri-O-benzoyl-alpha-D-ribofuranose
• Synonyms: 2-(1'-IMIDAZOYLSULFONYL)-1,3,5-TRI-O-BENZOYL-ALPHA-D-RIBOFURANOSE;2-(1'-Imidazoylsulfonyl)-1,2,5-tri-O-benzoyl-α-D-ribofuranose;1,2,5-Tri-O-benzoyl-2-(1'-imidazoylsulfonyl)-a-D-ribofuranose;1,3,5-Tri-O-benzoyl-2-O-(1'-imidazoylsulfonyl)-a-D-ribofuranose;2-(1'-IMidazoylsulfonyl)-1,3,5-tri-O-benzoyl-α-D-ribofuranose
• CAS NO: 97614-42-1
• Molecular Formula: C₂₉H₂₄N₂O₁₀S
• Molecular Weight: 592.57
• Mol File: 97614-42-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 749.9 ºC at 760 mmHg
• Flash Point: 407.3 ºC
• Appearance: /
• Density: 1.42 g/cm³
• CAS DataBase Reference: 2-(1'-Imidazoylsulfonyl)-1,3,5-tri-O-benzoyl-alpha-D-ribofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1'-Imidazoylsulfonyl)-1,3,5-tri-O-benzoyl-alpha-D-ribofuranose(97614-42-1)
• EPA Substance Registry System: 2-(1'-Imidazoylsulfonyl)-1,3,5-tri-O-benzoyl-alpha-D-ribofuranose(97614-42-1)

Safety Data

• Hazardous Substances Data: 97614-42-1(Hazardous Substances Data)

Usage

Uses

1,3,5-Tri-O-benzoyl-2-O-(1H-imidazol-1-ylsulfonyl)-alpha-D-ribofuranose is used in the preparation of clofarabine (nucleoside analog) for cancer treatment

Upstream product

• 288-32-4 1H-imidazole 
• 22224-41-5 1,3,5-tri-O-benzoyl-α-D-ribofuranoside 

Downstream Products

• 69123-98-4 fialuridine 
• 97614-46-5 1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl)-5-iodouracil 
• 97614-48-7 1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl)thymine 
• 97614-45-4 5-iodo-1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-β-D-arabinofuranosyl)uracil 
• 97614-47-6 1-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)thymine 
• 97614-44-3 2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide 
• 97614-43-2 1,3,5-tri-O-benzoyl-2-deoxy-2-fluoro-α-D-arabinofuranose 
• 314289-50-4 (2R,3S,4R,5R)-5-((benzoyloxy)methyl)-3-[¹⁸F]fluoro-tetrahydrofuran-2,4-diyl dibenzoate 
• 97614-50-1 2-O-(fluorosulfonyl)-1,3,5-tri-O-benzoyl-α-D-ribofuranose 
• 38491-60-0 β-phenyl hydroxypropionate 
• 97614-49-8 C₂₈H₂₆O₉ 

Relevant articles and documents

2'-FLUORO-4'-SUBSTITUTED NUCLEOSIDES, THE PREPARATION AND USE

The present invention provides 2'-fluorine-4'-substituted-nucleoside analogues or their pro-drugs or 5'-phosphate esters (including the pro-drugs of the 5'-phosphate esters), preparation methods and uses thereof. The compounds have the general formula as follows: wherein: R = CH3, CH, N3, C≡CH; R' = H, F; X = F, OH, NH2; Y = H, CH3, F, OH, NH2 The compounds are used in the synthesis of drugs for the treatment of virus infection, especially for the treatment of HBV, HCV or HIV infection.