97677-81-1

Basic information

• Product Name: 2-(2-THIENYL)BENZOYL CHLORIDE
• Synonyms: 2-THIEN-2YLBENZOYL CHLORIDE;2-(2-THIENYL)BENZOYL CHLORIDE;2-(Thien-2-yl)benzoyl chloride 97%;2-Thiophen-2-yl-benzoyl chloride;2-[2-(Chlorocarbonyl)phenyl]thiophene
• CAS NO: 97677-81-1
• Molecular Formula: C₁₁H₇ClOS
• Molecular Weight: 222.69
• Mol File: 97677-81-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 346.2 °C at 760 mmHg
• Flash Point: 163.2 °C
• Appearance: /
• Density: 1.305 g/cm³
• Vapor Pressure: 5.85E-05mmHg at 25°C
• Refractive Index: 1.614
• CAS DataBase Reference: 2-(2-THIENYL)BENZOYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-THIENYL)BENZOYL CHLORIDE(97677-81-1)
• EPA Substance Registry System: 2-(2-THIENYL)BENZOYL CHLORIDE(97677-81-1)

Safety Data

• Hazard Codes: C
• HazardClass: IRRITANT
• Hazardous Substances Data: 97677-81-1(Hazardous Substances Data)

Usage

General Description

2-(2-Thienyl)benzoyl chloride, also known as thienylbenzoyl chloride, is a chemical compound with the formula C14H9ClOS. It is a colorless to pale yellow liquid that is primarily used as a building block in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and dyes. 2-(2-THIENYL)BENZOYL CHLORIDE is a versatile intermediate that can undergo various chemical reactions, such as nucleophilic substitution and acylation, to form a wide range of derivatives. It is important to handle 2-(2-thienyl)benzoyl chloride with caution as it is a corrosive and toxic compound that can cause skin and eye irritation, and should be used in a well-ventilated area with proper personal protective equipment. Overall, this chemical is an important reagent in the field of organic chemistry, with diverse applications in the production of valuable compounds.

InChI:InChI=1/C11H7ClOS/c12-11(13)9-5-2-1-4-8(9)10-6-3-7-14-10/h1-7H

Upstream product

• 6072-49-7 2-(2'-carboxyphenyl)thiophene 
• 106851-53-0 2-(2’-bromophenyl)thiophene 
• 615-36-1 2-bromoaniline 
• 134-20-3 2-carbomethoxyaniline 
• 342-54-1 2-(methoxycarbonyl)benzenediazonium tetrafluoroborate 
• 17595-84-5 o-(2-thienyl)benzoic acid methyl ester 

Downstream Products

• 106183-47-5 α-diazo-2-(2-thienyl)acetophenone 
• 106183-37-3 methyl 3-<2'-(2''-thienyl)phenyl>3-oxopropanoate 
• 5706-08-1 4H-Indeno<1,2-b>thiophen-4-one 
• 194416-92-7 o-(5-formyl-2-thienyl)benzonitrile 
• 125610-77-7 1-cyano-2-(1-thiophenyl)-benzene 
• 91533-93-6 methyl 3-<2'-(2''-thienyl)phenyl>2-diazo-3-oxopropanoate 
• 154191-76-1 methyl diazo<2-(3,4,5-trichloro-2-thienyl)phenyl>acetate 
• 154191-78-3 methyl <2-(3,4,5,-trichloro-2-thienyl)phenyl>acetate 
• 154191-77-2 methyl <2-(2-thienyl)phenyl>acetate 
• 95219-19-5 6β-(2-thiophen-2-yl-benzoylamino)-penicillanic acid 

Relevant articles and documents

Simple and Efficient Large-scale Metal-free Synthesis of o-(5-Formyl-2-thienyl)benzonitrile and o-(5-Formyl-2-furyl)benzonitrile

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Potentially Aromatic Thiophenium Ylides. V. Reactions of Ethoxycarbonyl- (and Methoxycarbonyl)-2-(2-thienyl)phenylcarbene

In an attempt to make thiophenium ylides in which the ylide bond is part of a five-membered ring annulated to the α-side of the thiophene moiety, two alkoxycarbonyl substituted 2-(2-thienyl)phenylcarbenes have been made, with and without chlorine substituents in the remaining thiophene positions.With rhodium acetate as a catalyst the carbene without chlorines cyclized to the 3-position of the thiophene to give a fluorene analogue, whereas no cyclization was detected when the 3-position was blocked.

Potentyally Aromatic Thiophenium Ylides 4. Formation and Cyclization of Methyl and Methoxycarbonyl Substituted 2-(2'-Thienyl)benzoylcarbenes

The catalytic decomposition of methyl- and methoxycarbonyl substituted 2-(2'-diazoacetylphenyl)thiophenes has been studied.The products are accounted for by assuming a primary formation of bicyclic thiophenium ylides.The ylides rearrange to thiopyrans, sp