97691-66-2

Basic information

• Product Name: 2-Propyn-1-one, 1,3-bis(4-methylphenyl)-
• CAS NO: 97691-66-2
• Molecular Formula: C17H14O
• Molecular Weight: 234.298
• Mol File: 97691-66-2.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: 2-Propyn-1-one, 1,3-bis(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propyn-1-one, 1,3-bis(4-methylphenyl)-(97691-66-2)
• EPA Substance Registry System: 2-Propyn-1-one, 1,3-bis(4-methylphenyl)-(97691-66-2)

Safety Data

• Hazardous Substances Data: 97691-66-2(Hazardous Substances Data)

Upstream product

• 106-38-7 para-bromotoluene 
• 50978-45-5 3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide 
• 766-97-2 4-n-methylphenylacetylene 
• 104-87-0 4-methyl-benzaldehyde 
• 5524-56-1 ethyl 2-p-tolyl-2-oxoacetate 
• 108-88-3 toluene 
• 7163-50-0 (4-methylphenyl)(oxo)acetic acid 
• 3457-48-5 1,2-di(4-methylphenyl)-1,2-ethanedione 
• 615-37-2 ortho-methylphenyl iodide 
• 201230-82-2 carbon monoxide 
• 624-31-7 4-tolyl iodide 
• 99-94-5 p-Toluic acid 
• 104-85-8 para-methylbenzonitrile 
• 471-25-0 Propiolic acid 

Downstream Products

• 97691-65-1 4,6-di(p-tolyl)pyrimidin-2(1H)-one 
• 16112-20-2 3,5-di(4′-methylphenyl)isoxazole 
• 93330-77-9 3,5-di(4′-methylphenyl)-1H-pyrazole 
• 3594-36-3 1,3-bis(p-methylphenyl)-1,3-propanedione 
• 170647-13-9 2,4-bis-(4-methylbenzoyl)-1,5-di-p-tolylpentane-1,5-dione 
• 3457-48-5 1,2-di(4-methylphenyl)-1,2-ethanedione 
• 1590443-01-8 2,4-bis(4-methylphenyl)-1,1,1-trifluorobut-3-yn-2-ol 

Relevant articles and documents

Preparation method of acetylenic ketone compound

The invention provides a preparation method of an acetylenic ketone compound, which comprises the following step: reacting a compound with a structure as shown in a formula (II) with a compound with a structure as shown in a formula (III) under the action of a catalyst and an alkali to obtain the acetylenic ketone compound with a structure as shown in a formula (I). Compared with the prior art, the method has the advantages that the N-formyl saccharin is used as a carbon monoxide substitute reagent to realize carbonyl insertion reaction of bromo-aromatic hydrocarbon and a terminal alkyne compound under the catalysis of the palladium catalyst, so that the acetylenic ketone compound is obtained, the operation is simple, the raw materials and the reagent are easy to obtain, and the condition is mild; the method avoids the use of inflammable and explosive carbon monoxide gas and formic acid, oxalic acid and other acid corrosive carbon monoxide substitute reagents, the catalytic system is green and environment-friendly, the product is easy to separate and purify, and the high-purity acetylenic ketone compound can be efficiently prepared with a high yield.

Transition-metal-free C-C σ-bond activation of α-aryl ketones and subsequent Zn-catalyzed intramolecular cyclization: synthesis of tetrasubstituted furans

A highly atom-economical protocol for the synthesis of tetrasubstituted furans has been developed. This process is realized through the tandem reactions of Cs2CO3 promoted C-C σ-bond activation of α-aryl ketones followed by Zn-cataly

An easy access towards quinazolines via an improved protocol for ynones

A simple and convenient method has been developed to accomplish Pt/2,2'-bipyridyl catalyzed acyl Sonagashira coupling for the efficient synthesis of ynones. The reaction display significant tolerance to various functional groups and the methodology has be