97845-77-7

Basic information

• Product Name: 6H-Purin-6-one, 1,9-dihydro-9-[4-hydroxy-3-[[(4-methoxyphenyl)diphenylmethoxy]methyl] butyl]-2-[[(4-methoxyphenyl)diphenylmethyl]amino]-
• CAS NO: 97845-77-7
• Molecular Formula: C50H47N5O5
• Molecular Weight: 797.954
• Mol File: 97845-77-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 6H-Purin-6-one, 1,9-dihydro-9-[4-hydroxy-3-[[(4-methoxyphenyl)diphenylmethoxy]methyl] butyl]-2-[[(4-methoxyphenyl)diphenylmethyl]amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: 6H-Purin-6-one, 1,9-dihydro-9-[4-hydroxy-3-[[(4-methoxyphenyl)diphenylmethoxy]methyl] butyl]-2-[[(4-methoxyphenyl)diphenylmethyl]amino]-(97845-77-7)
• EPA Substance Registry System: 6H-Purin-6-one, 1,9-dihydro-9-[4-hydroxy-3-[[(4-methoxyphenyl)diphenylmethoxy]methyl] butyl]-2-[[(4-methoxyphenyl)diphenylmethyl]amino]-(97845-77-7)

Safety Data

• Hazardous Substances Data: 97845-77-7(Hazardous Substances Data)

Upstream product

• 39809-25-1 Penciclovir 
• 14470-28-1 mono-4-methoxytrityl chloride 
• 97845-59-5 2-amino-6-chloro-9-<2-(2,2-dimethyl-1,3-dioxan-5-yl)ethyl>purine 
• 6482-32-2 2-(hydroxymethyl)butane-1,4-diol 
• 7459-46-3 triethyl 1,1,2-ethanetricarboxylate 

Downstream Products

• 97845-81-3 9-<4-(benzoyloxy)-3-(hydroxymethyl)but-1-yl>guanine 
• 206067-85-8 N²-(p-anisyldiphenylmethyl)-9-[(4-fluoro)-3-p-anisyldiphenylmethoxy-methylbutyl]guanine 
• 206067-84-7 N²-(p-anisyldiphenylmethyl)-9-[(4-(p-toluenesulfonyloxy))-3-p-anisyldiphenylmethoxy-methyl-butyl]guanine 

Relevant articles and documents

Efficient synthesis of 9-(4-[18F]fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG) and 9-[(3-[18F]fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]FHPG)

A new, high radiochemical yield synthesis of [18F]FHBG and [18F]FHPG, the most popular imaging agents currently in use for monitoring gene therapy using positron emission tomography (PET), is reported in this work. Protection of sens

The new convenient synthesis of fluorinated Penciclovir analogues 9-(4-fluoro-3-hydroxymethylbutyl) guanine (FHBG) and 2-amino-6-fluoro-9-(4-hydroxy-3-hydroxymethylbutyl) purine (6-Fluoropenciclovir)

9-(4-Hydroxy-3-hydroxymethylbutyl) guanine (Penciclovir) is a potent and selective inhibitor of members of the herpes virus family. A new convenient synthesis of fluorinated Penciclovir analogues 9-(4-fluoro-3-hydroxymethylbutyl) guanine (FHBG) and 2-amin

Novel radiosynthesis of PET HSV-tk gene reporter probes [ 18F]FHPG and [18F]FHBG employing dual Sep-Pak SPE techniques

Positron emission tomography (PET) herpes simplex virus thymidine kinase (HSV-tk) gene reporter probes 9-[(3-[18F]fluoro-1-hydroxy-2-propoxy) methyl]guanine ([18F]FHPG) and 9-(4-[18F]fluoro-3- hydroxymethylbutyl)guanine ([18F]FHBG) were prepared by nucleophilic substitution of the appropriate tosylated precursors with [18F]KF/ Kryptofix 2.2.2 followed by a quick deprotection reaction and purification with a simplified dual Silica Sep-Pak solid-phase extraction (SPE) method in 15-30% radiochemical yield.