98105-63-6Relevant articles and documents
Syntheses and biological activities of new N1-aryl substituted quinolone antibacterials
Juergens, Jens,Schedletzky, Holger,Heisig, Peter,Seydel, Joachim K.,Wiedemann, Bernd,Holzgrabe, Ulrike
, p. 179 - 190 (2007/10/03)
A series of quinolones with a systematically varied substitution at the phenyl ring at N1 has been synthesized. Three lipophilicity descriptors (log K, log P, R(m)) and the pK(a) values have been determined as well as the microbiological activity: The MIC