98136-86-8

Basic information

• Product Name: 4-AMINO-3,5-DIIODOPYRIDINE
• Synonyms: 4-AMINO-3,5-DIIODOPYRIDINE;3,5-Diiodopyridin-4-amine;Pyridine,4-aMino-3,5-diiodo-
• CAS NO: 98136-86-8
• Molecular Formula: C₅H₄I₂N₂
• Molecular Weight: 345.91
• Mol File: 98136-86-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 135-136℃
• Boiling Point: 408.1 °C at 760 mmHg
• Flash Point: 200.6 °C
• Appearance: /
• Density: 2.679
• Vapor Pressure: 7.18E-07mmHg at 25°C
• Refractive Index: 1.784
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 4-AMINO-3,5-DIIODOPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-3,5-DIIODOPYRIDINE(98136-86-8)
• EPA Substance Registry System: 4-AMINO-3,5-DIIODOPYRIDINE(98136-86-8)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 98136-86-8(Hazardous Substances Data)

Usage

General Description

4-Amino-3,5-diiodopyridine is a chemical compound with the molecular formula C5H3I2N2. It is a derivative of pyridine and is used primarily in the synthesis of pharmaceuticals and agrochemicals. The compound has two iodine atoms and an amino group attached to the pyridine ring, making it a versatile building block for the creation of more complex molecules. 4-Amino-3,5-diiodopyridine is also used in organic synthesis and as a reagent in chemical reactions to form new carbon-carbon and carbon-nitrogen bonds. Its properties and applications make it an important compound in the field of organic chemistry.

InChI:InChI=1/C5H4I2N2/c6-3-1-9-2-4(7)5(3)8/h1-2H,(H2,8,9)

Upstream product

• 504-24-5 4-aminopyridine 

Downstream Products

• 931104-38-0 3,5-bis-[(triphenylsilanyl)-ethynyl]-pyridin-4-ylamine 
• 6052-72-8 5,6,9,10-tetrahydro-4H,8H-pyrido[3,2,1-ij][1,6]naphthyridine 
• 931104-39-1 3,5-bis-(2-triphenylsilanyl-ethyl)-pyridin-4-ylamine 

Relevant articles and documents

Process Optimization for the Large-Scale Preparation of (2 S,3 aR,7 aS)- tert-Butyl Hexahydro-2,5-methanopyrrolo[3,2- c]pyridine-1(4 H)-carboxylate, an Intermediate for Nicotinic Acetylcholine Receptor Agonists

An optimized large-scale synthesis of (2S,3aR,7aS)-tert-butyl hexahydro-2,5-methanopyrrolo[3,2-c]pyridine-1(4H)-carboxylate (1A), an important intermediate for nicotinic acetylcholine receptor agonists, is described. The key feature of the synthesis involves three transformations in a one-pot process, including debenzylation and ring hydrogenation of two fused bicyclic rings. Multihundred gram quantities of 1A were prepared.

TETRACYCLIC INHIBITORS OF JANUS KINASES

The present invention provides compounds that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases and cancer.