98168-21-9

Basic information

• Product Name: 1-Penten-3-ol, 2-methyl-, (S)-
• Synonyms: (S)-2-Methyl-pent-1-en-3-ol;(S)-3-methylpent-1-en-3-ol;(S)-2-methyl-1-penten-3-ol;(S)-(-)-2-methyl-1-penten-3-ol;(3S)-2-methylpent-1-en-3-ol
• CAS NO: 98168-21-9
• Molecular Formula: C6H12O
• Molecular Weight: 100.161
• Mol File: 98168-21-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1-Penten-3-ol, 2-methyl-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Penten-3-ol, 2-methyl-, (S)-(98168-21-9)
• EPA Substance Registry System: 1-Penten-3-ol, 2-methyl-, (S)-(98168-21-9)

Safety Data

• Hazardous Substances Data: 98168-21-9(Hazardous Substances Data)

Upstream product

• 78-85-3 2-methylpropenal 
• 557-20-0 diethylzinc 
• 925-90-6 ethylmagnesium bromide 
• 96481-55-9 2-methylpent-1-en-3-ol 

Downstream Products

• 98088-38-1 methyl (6S)-6-(benzyloxy)-2,5-dimethyl-4(Z)-enoate 
• 98088-41-6 (6S)-2,5-dimethyl-6-(benzyloxy)-4(Z)-octenal 
• 98088-36-9 (3R,4S)-3-methyl-4-(benzyloxy)-1-hexene-3-yl propionate 
• 98088-40-5 (6S)-2,5-dimethyl-6-(benzyloxy)-4(Z)-octen-1-ol 
• 98088-35-8 (3S)-3-(benzyloxy)-2-pentanone 
• 98088-37-0 (3S,4S)-4-Benzyloxy-3-methyl-hex-1-en-3-ol 
• 116505-81-8 (8S,8aS)-6-[(E)-(2S,6S)-6-Benzyloxy-1-iodo-2,5-dimethyl-oct-4-en-(E)-ylidene]-8-methyl-octahydro-indolizin-8-ol 
• 116561-36-5 (8S,8aS)-8-hydroxy-8-methyl-(6E)-<(2R,4E,6S)-6-(benzyloxy)-2,5-dimethyl-1-iodo-4-octenylidene>octahydroindolizine 
• 98088-45-0 (8S,8aS)-8-hydroxy-8-methyl-(6Z)-<(2R,4E,6S)-6-(benzyloxy)-2,5-dimethyl-4-octenylidene>octahydroindolizidine 
• 67054-00-6 (+)-pumiliotoxin A 
• 98088-34-7 (3S)-2-methyl-3-(benzyloxy)pentene 

Relevant articles and documents

Enantioselective synthesis of allylic alcohols via an oxazaborolidinium ion catalyzed diels-alder/retro-diels-alder sequence

A triflimide-activated oxazaborolidine catalyst successfully promoted the asymmetric Diels-Alder reaction of 9-methylanthracene with methacrolein in high regio- and enantioselectivity. The cycloadduct obtained was subsequently used as a chiral template to

An amino alcohol ligand for highly enantioselective addition of organozinc reagents to aldehydes: Serendipity rules

(matrix presented) Amino alcohol 4 (or its enantiomer) is prepared in two simple steps. Commercial (1R,2S)-2-amino-1,2-diphenylethanol is dialkylated with bis(2-bromoethyl) ether. Subsequent hydrogenation over 5% Rh on alumina in the presence of morpholine unexpectedly stops at the hexahydro derivative 4. Amino alcohol 4 promotes the enantioselective addition of diethylzinc to aldehydes at room temperature in up to 99% enantiomeric excess.

Formal total synthesis of (+)-methynolide

A formal total synthesis of (+)-methynolide was achieved in 23 steps highlighted by a crotylboration, a ring-closing metathesis, a Sharpless kinetic resolution of an allylic alcohol and a Takai reaction.