98395-62-1

Basic information

• Product Name: 4-(2-Aminoethoxy)-1-nitrobenzene hydrochloride
• Synonyms: 2-(4-Nitrophenoxy)ethylamine hydrochloride;4-(2-Aminoethoxy)-1-nitrobenzene hydrochloride;4-(2-Aminoethoxy)-1-nitrobenzene hydrochloride 98%;2-(4-Nitrophenoxy)ethanamine, HCl;4-(2-Aminoethoxy)-1-nitrobenzene, HCl;4-(2-Aminoethyoxy)-1-nitrobenzene, HCl;2-(4-Nitrophenoxy)ethanaMine hydrochloride;4-(2-Aminoethoxy)-1-nitrobenzenehydrochloride98%
• CAS NO: 98395-62-1
• Molecular Formula: C₈H₁₀N₂O₃*ClH
• Molecular Weight: 218.63754
• Product Categories: Amines;blocks;NitroCompounds
• Mol File: 98395-62-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 371.9°Cat760mmHg
• Flash Point: 178.7°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 6.81E-06mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-(2-Aminoethoxy)-1-nitrobenzene hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Aminoethoxy)-1-nitrobenzene hydrochloride(98395-62-1)
• EPA Substance Registry System: 4-(2-Aminoethoxy)-1-nitrobenzene hydrochloride(98395-62-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 98395-62-1(Hazardous Substances Data)

Usage

Description

4-(2-Aminoethoxy)-1-nitrobenzene hydrochloride is a nitrobenzene derivative with the molecular formula C8H11NO3Cl and a molecular weight of 203.63 g/mol. It is a pale yellow crystalline powder that is soluble in water and is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds.

Uses

Used in Pharmaceutical Industry:
4-(2-Aminoethoxy)-1-nitrobenzene hydrochloride is used as a chemical intermediate for the synthesis of various pharmaceuticals and organic compounds. Its unique structure and properties make it a valuable component in the development of new drugs and therapeutic agents.
Used in Research Applications:
4-(2-Aminoethoxy)-1-nitrobenzene hydrochloride is also used in research settings to study the properties and reactions of nitrobenzene derivatives. Its potential applications in medicine and other fields make it an important compound for scientific investigation.
It is important to handle 4-(2-Aminoethoxy)-1-nitrobenzene hydrochloride with care, as it may pose hazards if not handled properly.

InChI:InChI=1/C8H10N2O3.ClH/c9-5-6-13-8-3-1-7(2-4-8)10(11)12;/h1-4H,5-6,9H2;1H

Upstream product

• 824-78-2 4-nitrophenol sodium salt 
• 16365-27-8 2-(4-nitrophenoxy)ethanol 
• 98395-61-0 N-(2-(4-nitrophenoxy)ethyl)phthalimide 
• 22483-44-9 4-nitrophenoxyethyl 4-toluenesulfonate 

Downstream Products

• 1965-54-4 N-(2-hydroxyethyl)-4-nitroaniline 
• 28226-22-4 6-nitro-1,4-benzoxazine 
• 74032-78-3 N-(2-hydroxyethyl)-2-hydroxy-5-nitroaniline 

Relevant articles and documents

Regioselectivity of Photochemical and Thermal Smiles Rearrangements and Related Reactions of β-(Nitrophenoxy)ethylamines

The ortho, meta, and para isomers of β-(nitrophenoxy)ethylamine (1, 2, and 3, respectively) have been synthesized as hydrochloride salts.The corresponding ortho, meta, and para isomer of β-(nitrophenoxy)ethyl alcohol (4, 5, or 6, respectively), the Smiles rearrangement product, is formed cleanly in alkaline water by a thermal reaction from 1 or 3 and by a photochemical reaction from the triplet state of 2.Photolysis of 1 or 3 does not cause Smiles rearrangement; photoproducts recovered from 1 and 3 show that β-amino group in both cases bonds at the ring carbon atom adjacent to the side chain and meta to the nitro group.The contrast of these results with those reported for photo-Smiles rearrangements of similar systems containing NHPh as the attacking nucleophile and for intermolecular aromatic photosubstitution by alkylamines is discussed.The results support the recently proposed "energy gap" model for predicting regioseelctivity in heterolytic nucleophilic aromatic photosubstitution.