98398-22-2

Basic information

• Product Name: Benzeneethanamine, b-methyl-N-(2-phenylpropyl)-
• Synonyms: Bis-(2-phenyl-propyl)-amin;bis-(2-phenyl-propyl)-amine
• CAS NO: 98398-22-2
• Molecular Formula: C18H23N
• Molecular Weight: 253.387
• Mol File: 98398-22-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 180 °C (13 mmHg)
• Density: 0.977±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzeneethanamine, b-methyl-N-(2-phenylpropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanamine, b-methyl-N-(2-phenylpropyl)-(98398-22-2)
• EPA Substance Registry System: Benzeneethanamine, b-methyl-N-(2-phenylpropyl)-(98398-22-2)

Safety Data

• Hazardous Substances Data: 98398-22-2(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 124-40-3 dimethyl amine 
• 34713-70-7 2-Phenylpropanal 
• 1459-00-3 1-bromo-2-phenylpropane 
• 64-17-5 ethanol 
• 5841-70-3 phenyl(formyl)acetonitrile 
• 201230-82-2 carbon monoxide 
• 137406-88-3 Bis-(1-benzotriazol-1-yl-2-phenyl-propyl)-amine 

Relevant articles and documents

Dimethylamine as a Substrate in Hydroaminoalkylation Reactions

Transition-metal-catalyzed hydroaminoalkylations of alkenes have made great progress over the last decade and are heading to become a viable alternative to the industrial synthesis of amines through hydroformylation of alkenes and subsequent reductive amination. In the past, one major obstacle of this progress has been an inability to apply these reactions to the most important amines, methylamine and dimethylamine. Herein, we report the first successful use of dimethylamine in catalytic hydroaminoalkylations of alkenes with good yields. We also report applicability for a variety of alkenes to show the tolerance of the reaction towards different functional groups. Additionally, we present a catalytic dihydroaminoalkylation reaction using dimethylamine, which has never been reported before.

Chemoselective reductive alkylation of ammonia with carbonyl compounds: Synthesis of primary and symmetrical secondary amines

An efficient, general procedure for highly chemoselective reductive mono-alkylation of ammonia with ketones is reported. Treatment of ketones with ammonia in ethanol and titanium(IV) isopropoxide, followed by in situ sodium borohydride reduction, and a straightforward workup afforded primary amines in good to excellent yields. Reductive alkylation of ammonia with aldehydes, on the other hand, afforded the corresponding symmetrical secondary amines selectively.

Selective one-pot synthesis of symmetrically and unsymmetrically substituted amines via rhodium catalysed multiple alkylations of ammonia or primary amines under hydroformylation conditions

Symmetrically and unsymmetrically substituted secondary and tertiary amines are selectively prepared in high yields by a one-pot multiple alkylation procedure from ammonia or primary amines with styrenes and/or cyclic olefins, carbon monoxide and hydrogen