98436-74-9

Basic information

• Product Name: 4-Pyridinecarbonitrile,2-ethenyl-(9CI)
• Synonyms: 4-Pyridinecarbonitrile,2-ethenyl-(9CI);2-VINYLISONICOTINONITRILE
• CAS NO: 98436-74-9
• Molecular Formula: C8H6N2
• Molecular Weight: 130.14664
• Product Categories: PYRIDINE
• Mol File: 98436-74-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Pyridinecarbonitrile,2-ethenyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinecarbonitrile,2-ethenyl-(9CI)(98436-74-9)
• EPA Substance Registry System: 4-Pyridinecarbonitrile,2-ethenyl-(9CI)(98436-74-9)

Safety Data

• Hazardous Substances Data: 98436-74-9(Hazardous Substances Data)

Upstream product

• 10386-27-3 2-bromoisonicotinonitrile 
• 7486-35-3 tri-n-butyl(vinyl)tin 
• 33252-30-1 2-chloro-4-pyridinenitrile 
• 75927-49-0 pinacol vinylboronate 

Relevant articles and documents

Mur ligases inhibitors with azastilbene scaffold: Expanding the structure–activity relationship

Antibiotic resistance represents one of the biggest public health challenges in the last few years. Mur ligases (MurC–MurF) are involved in the synthesis of UDP-N-acetylmuramyl-pentapeptide, the main building block of bacterial peptidoglycan polymer. They are essential for the survival of bacteria and therefore important antibacterial targets. We report herein the synthesis and structure–activity relationships of Mur ligases inhibitors with an azastilbene scaffold. Several compounds showed promising inhibitory potencies against multiple ligases and one compound also possessed moderate antibacterial activity. These results represent a solid ground for further development and optimization of structurally novel antimicrobial agents to combat the rising bacterial resistance.

METABOTROPIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF

Compounds that modulate GluR5 activity and methods of using the same are disclosed.