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98454-39-8

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98454-39-8 Usage

Description

Trans-4-(phenylMethoxy)cyclohexanaMine is an organic compound that serves as a crucial reactant in the synthesis of various pharmaceutical compounds. It is characterized by its unique molecular structure, which features a cyclohexane ring with a phenylmethoxy group and an amine functional group. Trans-4-(phenylMethoxy)cyclohexanaMine plays a significant role in the development of medications with diverse therapeutic applications.

Uses

Used in Pharmaceutical Industry:
Trans-4-(phenylMethoxy)cyclohexanaMine is used as a key reactant in the synthesis of metabolites of Cilostazol (C441500), a potent phosphodiesterase III A (PDE3A) inhibitor with an IC50 of 0.2uM. Cilostazol exhibits antimitogenic, antithrombotic, vasodilatory, and cardiotonic properties in vivo, making it a valuable compound in the treatment of various cardiovascular conditions.
In the synthesis process, Trans-4-(phenylMethoxy)cyclohexanaMine contributes to the formation of the desired metabolites, which are responsible for the therapeutic effects of Cilostazol. Its presence in the synthesis reaction is essential for the production of an effective and safe medication for patients suffering from cardiovascular diseases.
Furthermore, the versatility of Trans-4-(phenylMethoxy)cyclohexanaMine as a reactant allows it to be employed in the development of other pharmaceutical compounds with different therapeutic targets. Its unique structure and reactivity make it a valuable building block in the creation of new drugs with potential applications in various medical fields.

Check Digit Verification of cas no

The CAS Registry Mumber 98454-39-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,4,5 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 98454-39:
(7*9)+(6*8)+(5*4)+(4*5)+(3*4)+(2*3)+(1*9)=178
178 % 10 = 8
So 98454-39-8 is a valid CAS Registry Number.

98454-39-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-phenylmethoxycyclohexan-1-amine

1.2 Other means of identification

Product number -
Other names TRANS-4-(BENZYLOXY)CYCLOHEXANAMINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:98454-39-8 SDS

98454-39-8Relevant articles and documents

Studies on 2-oxoquinoline derivatives as blood platelet aggregation inhibitors. IV. Synthesis and biological activity of the metabolites of 6-[4-(1-cyclohexyl-1H-5-tetrazolyl)butoxy]-2-oxo-1,2,3,4- tetrahydroquinoline (OPC-13013)

Nishi,Tabusa,Tanaka,Shimizu,Nakagawa

, p. 1140 - 1147 (2007/10/02)

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