98454-42-3

Basic information

• Product Name: (±)-trans-2-(benzyloxy)cyclohexanamine
• CAS NO: 98454-42-3
• Molecular Weight: 205.3
• Mol File: 98454-42-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (±)-trans-2-(benzyloxy)cyclohexanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-trans-2-(benzyloxy)cyclohexanamine(98454-42-3)
• EPA Substance Registry System: (±)-trans-2-(benzyloxy)cyclohexanamine(98454-42-3)

Safety Data

• Hazardous Substances Data: 98454-42-3(Hazardous Substances Data)

Upstream product

• 85761-38-2 (+/-)-trans-2-benzyloxycyclohexan-1-ol 
• 98454-36-5 N-((1R,2R)-2-Benzyloxy-cyclohexyl)-acetamide 
• 98454-36-5 N-((1R,2S)-2-Benzyloxy-cyclohexyl)-acetamide 
• 100-44-7 benzyl chloride 
• 18421-15-3 (±)-N-((1R,2R)-2-hydroxycyclohexyl)acetamide 
• 18421-15-3 (+/-)-N-(cis-2-hydroxy-cyclohexyl)-acetamide 

Downstream Products

• 40571-86-6 rac-(1R,2R)-2-(benzylamino)cyclohexanol 
• 931-16-8 (+/-)-trans-2-aminocyclohexanol 
• 141478-34-4 1-(N-benzylamino)-2-cyclohexanone 
• 121282-70-0 (+/-)-trans-1-hydroxy-2-tert-butoxycarbonylamino-cyclohexane 
• 87153-13-7 5-Chloro-pentanoic acid ((1S,2S)-2-benzyloxy-cyclohexyl)-amide 
• 87153-13-7 5-Chloro-pentanoic acid ((1R,2S)-2-benzyloxy-cyclohexyl)-amide 

Relevant articles and documents

Hybrid Organo- and Biocatalytic Process for the Asymmetric Transformation of Alcohols into Amines in Aqueous Medium

A hybrid organo- and biocatalytic system for the asymmetric conversion of racemic alcohols into amines was developed. Combining an organocatalyst, AZADO, an oxidant, NaOCl, and an enzyme, ω-transaminase, we implemented a one-pot oxidation-transamination sequential process in aqueous medium. The method showed broad substrate scope and was successfully applied to conventional secondary alcohols and sterically hindered β-substituted cycloalkanols, where a highly stereoselective dynamic asymmetric bioamination enabled us to set up both contiguous stereocenters with very high enantio- and diastereomeric ratio (>90% yield, >99% ee, and up to 49:1 dr).

Studies on 2-oxoquinoline derivatives as blood platelet aggregation inhibitors. IV. Synthesis and biological activity of the metabolites of 6-[4-(1-cyclohexyl-1H-5-tetrazolyl)butoxy]-2-oxo-1,2,3,4- tetrahydroquinoline (OPC-13013)

-