98489-36-2

Basic information

• Product Name: Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI)
• Synonyms: Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI);1-(4,6-dimethylpyridin-3-yl)methanamine(SALTDATA: 2HCl);(4,6-dimethylpyridine-3-yl)methanamine;(4,6-dimethylpyridin-3-yl)methanamine;1-(4,6-dimethyl-3-pyridinyl)methanamine
• CAS NO: 98489-36-2
• Molecular Formula: C₈H₁₂N₂
• Molecular Weight: 136.19428
• Product Categories: PYRIDINE
• Mol File: 98489-36-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI)(98489-36-2)
• EPA Substance Registry System: Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI)(98489-36-2)

Safety Data

• Hazardous Substances Data: 98489-36-2(Hazardous Substances Data)

Usage

General Description

Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI) is a chemical compound with the molecular formula C9H13N. It is a derivative of pyridine, and its structure includes a pyridine ring with a methyl group at the 2 and 4 positions, as well as an amino-methyl group at the 5 position. Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI) is used in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. It has various industrial applications, including as a building block for the synthesis of complex organic compounds. Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI) needs to be handled and stored with appropriate safety measures as it can be toxic and hazardous if not used properly. Overall, it is a versatile chemical with a wide range of applications in the chemical industry.

Upstream product

• 14237-71-9 2-chloro-4,6-dimethylnicotinonitrile 
• 6339-38-4 2-hydroxy-4-methoxymethyl-6-methyl-nicotinonitrile 
• 6623-21-8 3-cyano-4,6-dimethylpyridine 
• 6290-50-2 1-methoxypentane-2,4-dione 
• 769-28-8 2-hydroxy-4,6-dimethyl-3-carbonitrile 
• 72456-86-1 S-methyl-4,6-dimethyl-2-thiopyridine-3-carbonitrile 
• 18872-63-4 6-methyl-4-methoxymethyl-3-cyano-2-chloropyridine 

Downstream Products

• 490-28-8 pyridine-2,4,5-tricarboxylic acid 
• 1070790-89-4 (2R,3S)-3-(6-((4,6-dimethylpyridin-3-ylmethyl)amino)-9-isopropyl-9H-purin-2-ylamino)pentan-2-ol 

Relevant articles and documents

PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN

Disclosed are compounds, compositions and methods for treating pain, including inflammatory, visceral, and acute pain. Such compounds are represented by Formula (I) as follows: wherein A1, L1, D, and Q are defined herein.

PROKINETICIN 2 RECEPTOR ANTAGONISTS

The present invention relates to certain novel compounds of Formula (I): and methods for the treatment of prokineticin 2 or prokinetin 2 receptor mediated disorders.

Reductive desulfurization of 3-cyano-2-methylthiopyridines under the action of Raney nickel

The action of Raney nickel on substituted 3-cyano-2-methylthiopyridines was studied. Under conditions of catalytic hydrogenation, the reaction yields a mixture containing the aminosulfide resulting from reduction of the nitrile group with retention of the methylthio group, the nitrile resulting from elimination of the methylthio group, and the amine resulting from both reduction of the nitrile group and elimination of the methylthio group. Treatment of 3-cyano-2-methylthiopyridines with a large amount of Raney nickel under desulfurization conditions induces simultaneous elimination of the methylthio group and reduction of the nitrile group to the aminomethyl group. When reductive desulfurization is carried out in methanol or THF, primary amines are formed, while the reactions in isopropyl or ethyl alcohol give secondary or tertiary amines, which are formed upon alkylation of the amino group with alcohols.