98552-85-3Relevant articles and documents
Methylcarbonate and bicarbonate phosphonium salts as catalysts for the nitroaldol (Henry) reaction
Fabris, Massimo,Noe, Marco,Perosa, Alvise,Selva, Maurizio,Ballini, Roberto
experimental part, p. 1805 - 1811 (2012/04/17)
Phosphonium ionic liquids exchanged with bicarbonate and methylcarbonate anions (CILs) exhibit catalytic performances comparable to those of sterically hindered (non nucleophilic) organosuperbases such as DBU. At 25-50 °C, under solventless conditions, CI
P(RNCH2CH2)3N: An Efficient Promoter for the Nitroaldol (Henry) Reaction
Kisanga, Philip B.,Verkade, John G.
, p. 4298 - 4303 (2007/10/03)
The use of catalytic amounts of the proazaphosphatranes P(MeNCH2CH2)3N, P(i-PrNCH2CH2)3N and P(HNCH2CH2)(i-PrNCH2CH2) 2N as nonionic bases in the reaction of nitroalkanes with carbonyl compounds is reported. The reaction proceeds at room temperature in the presence of 2.2 equiv of magnesium sulfate to produce the corresponding β-nitroalkanols in generally superior yields. Aldehydes react quantitatively in 5-60 min, whereas ketones require up to 3 h to react with nitromethane and up to 7 h for the reaction of ketones with higher nitroalkanes.