98619-37-5

Basic information

• Product Name: 1,3-dimethyl-2,5-dioxoimidazolidin-4-yl benzoate
• Synonyms: 1,3-dimethyl-2,5-dioxoimidazolidin-4-yl benzoate
• CAS NO: 98619-37-5
• Molecular Weight: 248.238
• Mol File: 98619-37-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3-dimethyl-2,5-dioxoimidazolidin-4-yl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dimethyl-2,5-dioxoimidazolidin-4-yl benzoate(98619-37-5)
• EPA Substance Registry System: 1,3-dimethyl-2,5-dioxoimidazolidin-4-yl benzoate(98619-37-5)

Safety Data

• Hazardous Substances Data: 98619-37-5(Hazardous Substances Data)

Upstream product

• 64732-10-1 5-hydroxy-1,3-dimethylimidazolidine-2,4-dione 
• 93-97-0 benzoic acid anhydride 
• 98619-34-2 N,N'-dimethyl-5-hydroxy-5-benzylhydantoin 
• 98-88-4 benzoyl chloride 

Relevant articles and documents

A Cascade Approach for the Synthesis of 5-(Indol-3-yl)hydantoin: An Application to the Total Synthesis of (±)-Oxoaplysinopsin B

A cascade approach to the synthesis of 5-(indol-3-yl)hydantoin framework has been developed by the reaction of indole with glyoxylic acid/pyruvic acid under a deep eutectic solution, (+)-tartaric acid-dimethylurea. N,N′-Dimethylurea from a deep eutectic solution functions as a reactant as well as a solvent mixture. Isolation of the intermediate, 5-hydroxyhydantoin, and its reaction with indole provides the mechanistic evidence for this reaction. This method was successfully applied in the first total synthesis of an alkaloid, (±)-oxoaplysinopsin B, with an overall yield of 48%.