98735-19-4Relevant articles and documents
Reconstruction of Ring A of 3,4-Dinor-2,5-seco Steroids
Boar, Robin B.,Patel, Arvind C.
, p. 1201 - 1204 (2007/10/02)
Methods for the reconversion of 3,4-dinor-2,5-seco steroids into the parent 4-en-3-one systems are discussed.In an efficient route, reaction of 17β-acetoxy-5,5-ethylenedioxy-3,4-dinor-2,5-secoandrostan-2-al with ethoxyvinyl-lithium led to the corresponding 2ξ-hydroxy-3-one.Acetylation followed by treatment with zinc dust in acetic acid then gave testosterone acetate.A similar series of reactions was performed in the progesterone series.