98819-09-1

Basic information

• Product Name: picropolygamain
• Synonyms: picropolygamain
• CAS NO: 98819-09-1
• Molecular Formula: C20H16 O6
• Molecular Weight: 352.34
• Mol File: 98819-09-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 537.3°Cat760mmHg
• Flash Point: 238.9°C
• Appearance: /
• Density: 1.44g/cm³
• CAS DataBase Reference: picropolygamain(CAS DataBase Reference)
• NIST Chemistry Reference: picropolygamain(98819-09-1)
• EPA Substance Registry System: picropolygamain(98819-09-1)

Safety Data

• Hazardous Substances Data: 98819-09-1(Hazardous Substances Data)

Upstream product

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• 2635-13-4 1,2-(methylenedioxy)-4-bromobenzene 
• 861205-66-5 (Z)-1-benzo[1,3]dioxol-5-yl-3-tert-butoxypropenone 
• 120-57-0 piperonal 
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• 2606-51-1 3,4-Methylenedioxybenzyl bromide 

Relevant articles and documents

Asymmetric Chemoenzymatic Synthesis of (?)-Podophyllotoxin and Related Aryltetralin Lignans

(?)-Podophyllotoxin is one of the most potent microtubule depolymerizing agents and has served as an important lead compound in antineoplastic drug discovery. Reported here is a short chemoenzymatic total synthesis of (?)-podophyllotoxin and related aryltetralin lignans. Vital to this approach is the use of an enzymatic oxidative C?C coupling reaction to construct the tetracyclic core of the natural product in a diastereoselective fashion. This strategy allows gram-scale access to (?)-deoxypodophyllotoxin and is readily adaptable to the preparation of related aryltetralin lignans.

PROCESS TO OBTAIN SYNTHETIC AND SEMI-SYNTHETIC LIGNAN DERIVATIVES, THEIR ANTIPARASITIC ACTIVITIES AND CORRESPONDING PHARMACEUTICAL FORMULATIONS, INCLUDING THE THERAPEUTIC METHOD USING SAID LIGNAN FOR THE TREATMENT OF PARASITOSIS

The invention refers to a process to obtain synthetic and semi-synthetic derivatives of lignans, especially dibenzylbutyrolactonic, tetrahydrofuranic, aryltetralynic, furofuranic and dibenzocyclooctanic lignans obtained by means of partial synthesis and/o