99-11-6 Usage
Description
Citrazinic acid, also known as 2,6-dihydroxypyridine-4-carboxylic acid, is an organic compound with the chemical formula C6H5NO4. It is a yellow powder and is used as a key intermediate in the synthesis of various organic compounds.
Uses
Used in Chemical Synthesis:
Citrazinic acid is used as a key intermediate for the preparation of 2,6-dibromo-4-(hexoxymethyl)pyridine. It is also used to synthesize the derivatives of oxazinones and pyrimidinones.
Used in Pharmaceutical Industry:
Citrazinic acid is used as a building block for the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be used in the development of new drugs and drug candidates.
Used in Research and Development:
Citrazinic acid is used in research and development for the study of its chemical properties and potential applications. It is a valuable compound for researchers working in the fields of organic chemistry, medicinal chemistry, and drug discovery.
Purification Methods
The acid is normally a yellow powder with a greenish shade, but is white when ultra pure and turns blue on long standing. It is insoluble in H2O but slightly soluble in hot HCl and soluble in alkali or carbonate solutions. It is purified by precipitation from alkaline solutions with dilute HCl, and dried in a vacuum over P2O5. The ethyl ester has m 232o (evacuated tube) and a pKa of 4.81 in MeOCH2CH2OH [IR: Pitha Coll Czech Chem Comm 28 1408 1963]. [Beilstein 22/7 V 24.]
Check Digit Verification of cas no
The CAS Registry Mumber 99-11-6 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 9 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 99-11:
(4*9)+(3*9)+(2*1)+(1*1)=66
66 % 10 = 6
So 99-11-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H5NO4/c8-4-1-3(6(10)11)2-5(9)7-4/h1-2H,(H,10,11)(H2,7,8,9)/p-1
99-11-6Relevant articles and documents
Synthesis method of citrazinic acid
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Paragraph 0010; 0012; 0013, (2018/07/06)
The invention belongs to the technical field of compound preparation and particularly relates to a synthesis method of citrazinic acid. The method adopts a hydrothermal reaction method of citric acidand urea and particularly comprises the steps of dissolving citric acid and urea in deionized water, performing ultrasound dispersion and intensive mixing, performing a hydrothermal reaction under a certain temperature condition in a reaction kettle, performing high-speed centrifugation on reaction liquid at last, removing a supernate, and drying an obtained yellow precipitate, namely a citrazinicacid product with good color, high yield and high purity. The method is mild in reaction condition, and simple to operate; one-step sulfuric acid hydrolysis is required only, and the product is highin purity (greater than 96%) and productivity (70-85%).