99120-49-7 Usage
Description
GLP-2 (HUMAN), also known as Glucagon-like peptide 2, is a 33-amino acid peptide hormone that belongs to the pro-glucagon gene family. It is released by enteroendocrine L cells in the small and large intestinal circulation. GLP-2 plays a crucial role in regulating gastrointestinal function and promoting intestinal growth and repair.
Used in Pharmaceutical Industry:
GLP-2 (HUMAN) is used as a therapeutic agent for promoting intestinal growth and repair. It has been used for injection in chickens to determine the effects of GLP-2 on the weight and morphology of small intestines, indicating its potential use in treating conditions related to intestinal health and function.
Used in Research Applications:
GLP-2 (HUMAN) is used as a research tool for studying the mechanisms of intestinal growth, repair, and function. It helps researchers understand the role of GLP-2 in gastrointestinal health and develop new therapeutic strategies for treating related disorders.
Biochem/physiol Actions
Glucagon-like peptide 2 (GLP-2) influences the functionality of gastrointestinal tract by participating in the feedback loop to the brain for the control of food intake. It also controls digestion and absorption, and has tropic effects post chemotherapy injury or surgical resection. This peptide is also responsible for epithelial cell proliferation of the small bowel. Studies in rats show that this peptide enhances the effects of the ileal-brake hormones, GLP-1 and peptide YY. It also negatively regulates gastrointestinal motility and secretion. Thus, it has potential as a therapeutic agent in short-bowel syndrome.
Check Digit Verification of cas no
The CAS Registry Mumber 99120-49-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,1,2 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 99120-49:
(7*9)+(6*9)+(5*1)+(4*2)+(3*0)+(2*4)+(1*9)=147
147 % 10 = 7
So 99120-49-7 is a valid CAS Registry Number.