99274-32-5

Basic information

• Product Name: 1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-phenyl-, (2S,4S,5R)-
• CAS NO: 99274-32-5
• Molecular Formula: C11H12O4
• Molecular Weight: 208.214
• Mol File: 99274-32-5.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-phenyl-, (2S,4S,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-phenyl-, (2S,4S,5R)-(99274-32-5)
• EPA Substance Registry System: 1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-phenyl-, (2S,4S,5R)-(99274-32-5)

Safety Data

• Hazardous Substances Data: 99274-32-5(Hazardous Substances Data)

Upstream product

• 80924-06-7 1,3-O-benzylidene D-arabitol 
• 3006-41-5 4,6-O-benzylidene-α,β-D-galactopyranose 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 100-52-7 benzaldehyde 
• 59-23-4 D-Galactose 
• 488-82-4 D-Arabitol 
• 53131-06-9 1,3-O-benzylidene-D-arabinitol 
• 10257-28-0 D-Galactose 

Downstream Products

• 951787-30-7 1,1-dibenzyl-2-(((2S,4R,5R)-5-hydroxy-2-phenyl-1,3-dioxan-4-yl)methylene)hydrazine 
• 150162-78-0 (2R,3S)-1,3-O-benzylidene-1,2,3-octadecanetriol-4-one 
• 150162-79-1 (2R,3S,4R)-1,3-O-benzylidene-4-methyloctadecane-1,2,3,4-tetrol 
• 150162-86-0 (2R,3S,4S)-1,3-O-benzylidene-4-methyloctadecane-1,2,3,4-tetrol 
• 150162-87-1 (2R,3S,4S)-1,3-O-benzylidene-2-(tert-butyldimethylsilyloxy)-4-methyloctadecane-1,3,4-triol 
• 150162-80-4 (2R,3S,4R)-1,3-O-benzylidene-2-(tert-butyldimethylsilyloxy)-4-methyloctadecane-1,3,4-triol 
• 303752-90-1 1,3-O-benzylidene-(D-arabino/L-xylo)-1,2,3,4-octadecanetetrol 
• 1448722-25-5 (2R,3R,4R,5R)-1,3-[(S)-benzylidenedioxy]-5,9-dimethyl-5-vinyldec-8-ene-2,4-diol 
• 1448722-26-6 (2R,3R,4R,5S)-1,3-[(S)-benzylidenedioxy]-5,9-dimethyl-5-vinyldec-8-ene-2,4-diol 
• 117168-55-5 (2R,3R,4R)-1,3-O-benzylidene-1,2,3,4-octadecanetetrol 
• 117168-65-7 (2R,3R,4S)-1,3-O-benzylidene-1,2,3,4-octadecanetetrol 
• 117168-66-8 (2S,4R,5R)-4-[(R)-1-hydroxypentadecyl]-2-phenyl-1,3-dioxan-5-yl methanesulfonate 
• 745041-30-9 (2R,3S,4R)-1,3-O-benzylidene-2-O-methanesulfonyl-1,2,3,4-nonanetetrol 
• 1333920-08-3 1,3-O-benzylidene-2-O-methanesulfonyl-4-O-p-nitrobenzoyl-D-arabino-1,2,3,4-nonanetetrol 

Relevant articles and documents

An Improved, Versatile, and Easily Scalable Synthesis of Sphingomyelins: Application to Stable Isotope Labeling

With a view to make conveniently labeled mass spectrometry standards available, a set of deuterated sphingomyelins were prepared by a new expedient, flexible, robust, scalable, and high-yielding synthetic scheme starting from 2-azido-3- O -benzoylsphingos

4,5-Cis Unsaturated α-GalCer Analogues Distinctly Lead to CD1d-Mediated Th1-Biased NKT Cell Responses

The total synthesis of 4,5-cis unsaturated α-GalCer analogues was achieved, and their immune-response altering activity was assessed in vitro as well as in vivo in mice. Using glycosyl iodide as a glycosyl donor, construction of the sphingosine unit was shortened by four steps and single α-stereoselectivity was achieved in good yield (67%). With regard to the therapeutic use of α-GalCer, the novel analogues (1b and 1c) distinctly induced a Th1-biased cytokine response, avoiding induction of a contradictory response and overstimulation.

First total synthesis of theopederin B

Total synthesis of theopederin B, isolated from marine sponge, was accomplished by coupling pederic acid, as the left half, with trioxodecaline amine as the right half. Key reactions for synthesizing the amine were SmI2-promoted Reformatsky rea