99293-89-7

Basic information

• Product Name: N-benzoyl-1,2-dihydroquinolin-4(3H)-one
• Synonyms: N-benzoyl-1,2-dihydroquinolin-4(3H)-one
• CAS NO: 99293-89-7
• Molecular Weight: 251.285
• Mol File: 99293-89-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-benzoyl-1,2-dihydroquinolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzoyl-1,2-dihydroquinolin-4(3H)-one(99293-89-7)
• EPA Substance Registry System: N-benzoyl-1,2-dihydroquinolin-4(3H)-one(99293-89-7)

Safety Data

• Hazardous Substances Data: 99293-89-7(Hazardous Substances Data)

Upstream product

• 24364-35-0 N-benzoyl-N-phenyl-β-alanine 
• 16078-38-9 N-benzoyl-1,2,3,4-tetrahydroquinoline 
• 615-43-0 2-iodophenylamine 
• 125812-44-4 2-(2-(hydroxymethyl)ethynyl)aniline 
• 4295-36-7 2,3-dihydroquinolin-4(1H)-one 
• 98-88-4 benzoyl chloride 
• 21911-84-2 methyl 3-(phenylamino)propanoate 
• 635-46-1 1,2,3,4-tetrahydroisoquinoline 

Downstream Products

• 93-89-0 benzoic acid ethyl ester 
• 1034193-48-0 1-benzoyl-3,3-dimethyl-2,3-dihydro-1H-quinolin-4-one 
• 24206-41-5 (4-hydroxy-3,4-dihydroquinolin-1(2H)-yl)(phenyl)methanone 

Relevant articles and documents

Two transition-metal-modified Nb/W mixed-addendum polyoxometalates for visible-light-mediated aerobic benzylic C–H oxidations

The visible-light-induced selective oxidation of ubiquitous C–H bonds into valuable C=O bonds under aerobic conditions is one of the most attractive approaches for the construction of carbonyl-containing molecules. In this work, two transition metal-containing Nb/W mixed-addendum POMs dimers with the formula of K2Na2H5[(Fe(H2O)4)3(P2W15Nb3O62)2]?24H2O (POM[Fe]) and K2Na3H4[(Cr(H2O)4)3(P2W15Nb3O62)2]?32H2O (POM[Cr]) have been synthesized and characterized by various analytical and spectral techniques. POM[Fe] was proved to be an efficient photocatalyst for benzylic C–H oxidation under visible light and using oxygen as an oxidant to produce the corresponding carbonyl complex in good yields. A plausible mechanism involving superoxide radical was proposed for the catalytic reaction. POM[Fe] showed good reusability in the recycling experiments. IR spectroscopy and XRD analysis indicate that POM[Fe] can retain its integrity after catalysis.

4-IMIDAZOLYL-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS ALDOSTERONE/11-BETA-HYDROXYLASE INHIBITORS

The present invention provides a compound of formula (I), said compound is inhibitor of aldosterone synthase, and/or 11beta-hydroxylase (CYP11B1), and thus can be employed for the treatment of a disorder or disease mediated by aldosterone synthase and/or CYP11B1. Finally, the present invention also provides a pharmaceutical composition.