99789-57-8

Basic information

• Product Name: N-(4-methoxy-benzyl)-phenothiazine
• Synonyms: N-(4-methoxy-benzyl)-phenothiazine
• CAS NO: 99789-57-8
• Molecular Weight: 319.427
• Mol File: 99789-57-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-methoxy-benzyl)-phenothiazine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxy-benzyl)-phenothiazine(99789-57-8)
• EPA Substance Registry System: N-(4-methoxy-benzyl)-phenothiazine(99789-57-8)

Safety Data

• Hazardous Substances Data: 99789-57-8(Hazardous Substances Data)

Upstream product

• 92-84-2 10H-phenothiazine 
• 824-94-2 p-methoxybenzyl chloride 
• 583-55-1 1-Bromo-2-iodobenzene 
• 6320-02-1 o-bromothiophenol 
• 2393-23-9 4-methoxy-benzylamine 

Relevant articles and documents

Palladium-catalyzed three-component approach to promazine with formation of one carbon-sulfur and two carbon-nitrogen bonds

(Chemical Presented) Zip it up! The use of a Pd/dppf catalyst gives access to the tricyclic phenothiazine scaffold starting from 1-bromo-2-iodobenzenes, aliphatic or aromatic amines, and 2-bromothiophenols in a single reaction flask (see scheme; dppf=1,1′-bis(diphenylphosphanyl) ferrocene; dba=dibenzylidineacetone). This transformation involves thioether formation and subsequent intermolecular and intramolecular aryl amination reactions. The reaction occurs in good overall yield and selectivity.