99822-80-7

Basic information

• Product Name: ethyl 4-phenylthiazole-5-carboxylate
• Synonyms: ethyl 4-phenyl-1,3-thiazole-5-carboxylate;5-Thiazolecarboxylic acid, 4-phenyl-, ethyl ester
• CAS NO: 99822-80-7
• Molecular Formula: C₁₂H₁₁NO₂S
• Molecular Weight: 233.28624
• Mol File: 99822-80-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 90 °C
• Boiling Point: 390.1±30.0 °C(Predicted)
• Appearance: /
• Density: 1.216±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 0.29±0.10(Predicted)
• CAS DataBase Reference: ethyl 4-phenylthiazole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-phenylthiazole-5-carboxylate(99822-80-7)
• EPA Substance Registry System: ethyl 4-phenylthiazole-5-carboxylate(99822-80-7)

Safety Data

• Hazardous Substances Data: 99822-80-7(Hazardous Substances Data)

Upstream product

• 64399-23-1 ethyl 4-phenyl-2-aminothiazole-5-carboxylate 
• 115-08-2 thiocarboxamide 
• 55919-47-6 ethyl 2-bromo-3-oxo-3-phenylpropionate 

Downstream Products

• 1047672-26-3 (3R)-1-azabicyclo[2.2.2]oct-3-yl (4-phenyl-1,3-thiazol-5-yl)carbamate hydrochloride 
• 99822-84-1 4-phenyl-1,3-thiazole-5-carboxylic acid 

Relevant articles and documents

Novel quinuclidinyl heteroarylcarbamate derivatives as muscarinic receptor antagonists

Herein, we describe the synthesis and pharmacological profiles of novel quinuclidinyl heteroarylcarbamate derivatives. Among them, the quinuclidin-4-yl thiazolylcarbamate derivative ASP9133 was identified as a promising long-acting muscarinic antagonist (LAMA) showing more selective inhibition of bronchoconstriction against salivation and more rapid onset of action in a rat model than tiotropium bromide.