99839-93-7Relevant articles and documents
Electrochemical Synthesis of Cyanoformamides from Trichloroacetonitrile and Secondary Amines Mediated by the B12Derivative
Moniruzzaman, Mohammad,Yano, Yoshio,Ono, Toshikazu,Shimakoshi, Hisashi,Shiota, Yoshihito,Yoshizawa, Kazunari,Hisaeda, Yoshio
, p. 16134 - 16143 (2021/07/19)
The B12derivative, heptamethyl cobyrinate, -mediated electrochemical synthesis of cyanoformamides has been developed. Aerobic oxygenation of the carbon-centered radical initiatedin situgeneration of the reactive acyl chloride intermediate, whic
Solvent-Free Synthesis of Cyanoformamides from Carbamoyl Imidazoles
Nugent, Jeremy,Campbell, Sarah G.,Vo, Yen,Schwartz, Brett D.
, p. 5110 - 5118 (2017/09/23)
A straightforward and solvent-free synthesis of various secondary and tertiary cyanoformamides from carbamoyl imidazoles and TMSCN has been developed. Both cyclic and acyclic carbamoyl imidazoles react smoothly to form the relevant cyanoformamides in excellent yields, often within minutes.
Synthesis of 2-oxindoles via 'transition-metal-free' intramolecular dehydrogenative coupling (IDC) of sp2 C-H and sp3 C-H bonds
Kumar, Nivesh,Ghosh, Santanu,Bhunia, Subhajit,Bisai, Alakesh
supporting information, p. 1153 - 1169 (2016/07/06)
The synthesis of a variety of 2-oxindoles bearing an all-carbon quaternary center at the pseudo benzylic position has been achieved via a 'transition-metal-free' intramolecular dehydrogenative coupling (IDC). The construction of 2-oxindole moieties was carried out through formation of carbon-carbon bonds using KOt-Bu-catalyzed one pot C-alkylation of β-N-arylamido esters with alkyl halides followed by a dehydrogenative coupling. Experimental evidences indicated toward a radical-mediated path for this reaction.