Benzene,1-chloro-4-(methylsulfinyl)- MSDS CasNo.934-73-6

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CAS : 934-73-6 ProductName : p-Chlorophenyl methyl sulfoxide

MSDS

 Sulfoxide, p-chlorophenyl methyl

CAS

 934-73-6

SYNONYMS

 * Benzene, 1-chloro-4-(methylsulfinyl)-
* 1-Chloro-4-(methylsulfinyl)benzene
* p-Chlorophenyl methyl sulfoxide
* 4-Chlorophenyl methyl sulfoxide
* Methyl 4-chlorophenyl sulfoxide

Catalog of Chemical Suppliers, Buyers, Custom Synthesis Companies And Equipment Manufacturers
[ Sulfoxide, p-chlorophenyl methyl 934-73-6 ]

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WS2670000
CHEMICAL NAME           : Sulfoxide, p-chlorophenyl methyl
CAS REGISTRY NUMBER     : 934-73-6
BEILSTEIN REFERENCE NO. : 2041795
REFERENCE               : 4-06-00-01582 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : C7-H7-Cl-O-S
MOLECULAR WEIGHT        : 174.65
WISWESSER LINE NOTATION : OS1&R DG
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Benzene, 1-chloro-4-(methylsulfinyl)-
   * 1-Chloro-4-(methylsulfinyl)benzene
   * p-Chlorophenyl methyl sulfoxide
   * 4-Chlorophenyl methyl sulfoxide
   * Methyl 4-chlorophenyl sulfoxide
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Severe
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD-A082-824
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg
REACTION SEVERITY       : Severe
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD-A082-824
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 463 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD-A082-824
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5600 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 12,369,1993
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 328 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 12,369,1993
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5600 mg/kg/28D-C
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - death
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD-A082-824
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3413 mg/kg/91D-C
TOXIC EFFECTS :
   Liver - changes in liver weight
   Kidney, Ureter, Bladder - changes in bladder weight
   Blood - normocytic anemia
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD-A082-824
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6825 mg/kg/91D-C
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - death
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD-A082-824
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17242 mg/kg/28D-C
TOXIC EFFECTS :
   Liver - other changes
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - death
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 12,377,1993
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 280 mg/kg/14D-C
TOXIC EFFECTS :
   Liver - changes in liver weight
   Gastrointestinal - hypermotility, diarrhea
   Kidney, Ureter, Bladder - changes in bladder weight
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD-A082-824

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   On EPA IRIS database

 
                            *** END OF RECORD ***

P-CHLOROPHENYL METHYL SULFOXIDE